K.C. Cooper, a high school math whiz and karate black-belt, learns that her parents are spies when they recruit her to join them in the secret government agency, The Organization. While she now has the latest spy gadgets at her disposal, K.C. has a lot to learn about being a spy, including keeping her new gig a secret from her best friend Marisa. Together, K.C. and her parents, Craig and Kira, and her younger siblings, Ernie and Judy (a humanoid robot), try to balance everyday family life while on undercover missions, near and far, to save the world.

Leo is an ordinary teenager who has moved into a high-tech "smart'' house with his mother, inventor stepfather and Eddy, the computer that runs the house. Leo's life becomes less ordinary when, one day, he discovers a secret underground lab that houses three experiments: superhuman teenagers. The trio -- Adam, the strong one, Bree, the fast one and Chase, the smart one -- convinces Leo and his parents to let them leave their lab and join Leo at school, where they try to fit in while having to manage their unpredictable bionic strengths. As Leo figures out a way to keep his new pals' bionic abilities a secret, they help him build self-confidence.