Perpetually single Frankie decides to give up on men in favor of going all-in as a “dog mom" to her adopted dog, Tucker. But sparks fly when Frankie meets Jack, the veterinarian who rescues her dog from near death. They seem destined to be together, but there's one problem: Jack is already engaged.
Janet Flanders is a small-town, unsophisticated young woman who is seduced by the fantasy of romantic love; she believes that someday her prince will come to sweep her away. Then she meets handsome Brett Becker; she believes she's found the man of her dreams -- little suspecting he is engaged to marry a wealthy socialite. Deep into her illusion that Brett loves her, she moves to Chicago to be closer to him, deluge him with calls and love notes, tells her family about her boyfriend Brett, and buys an engagement ring. Her obsession with him leads her from intrigue and eventually to murder.
Mark, Jasper and Lily are high school friends now in their early twenties. Mark is gay, living with Lily (his high school girlfriend), while Jasper is straight and soon to be married. A cynical and bitter trio barely connected by their past friendship, they reunite for the annual public Halloween celebration in San Francisco's Castro district.