In 2071, roughly fifty years after an accident with a hyperspace gateway made the Earth almost uninhabitable, humanity has colonized most of the rocky planets and moons of the Solar System. Amid a rising crime rate, the Inter Solar System Police (ISSP) set up a legalized contract system, in which registered bounty hunters, also referred to as "Cowboys", chase criminals and bring them in alive in return for a reward.

In a futuristic world almost barren of life, mankind is confined to mechanized domed cities where A.I.’s control all aspects of life. In this world, humans are no longer born, they are manufactured in a production line; and alongside them live androids known as autoreivs. Within one of these domed sanctuaries named Romdeau lives Re-l Mayer, one of a few citizens who aren’t entirely prevented from thinking. Her grandfather's prominent position and the affection of the scientist Daedalus have left her more free will than is normally allowed, but Re-l has started to question the sanctity of the city and the citizens' perfect way of life. With mysterious beings known as proxies causing havoc and a man named Vincent causing great influence on her life, Re-l must travel outside of the city to find the answers she seeks and discover the mystery behind "the awakening".

Kaname Chidori’s one of the most popular girls at her high school – unfortunately, it’s her growing popularity off campus she should be worrying about. Unbeknownst to Kaname, terrorists are plotting her abduction, believing she possesses the rare and coveted abilities of “the Whispered.” That’s where Sousuke Sagara enters the picture. He’s a hotshot soldier from the clandestine counter-terrorist organization known as Mithril – and he’s going undercover at Kaname’s school to try and keep her safe. He may be an ace in the cockpit of an Arm Slave mech, but there’s no training in the world that could prepare him for the warzone of high school.

Forty years ago, the minds of Paradigm City's inhabitants were wiped clean of all recollections of the past. Now, ruled by a powerful corporation and cut off from the rest of the world by desolate wastelands, Paradigm has become a virtual police state where Negotiators like Roger Smith keep the wheels of progress, commerce, and society turning.

Across the ocean on the tiny island kingdom of Barou the ancient god Neo Ranga awakens from his slumber. He is mysteriously drawn to Tokyo, and the three beautiful sisters - Minami, Ushio, and Yuuhi - who are unwittingly linked to the monster.

But instead of rolling out the red carpet, the military rolls out the weaponry, and things start to get nasty. The plot thickens: Why is Neo Ranga driven to Tokyo? Is he a messenger with a warning for humankind, or just a big boy out for a good time? And what's behind Ranga's mysterious eyes?

Since the graduation of the senior members of the club, Takezou ends up being the sole member of the "Koto" (traditional Japanese string instrument) club. Now that the new school year has begun, Takezou will have to seek out new members into the club, or the club will become terminated. Out of nowhere, a new member barges into the near-abandoned club room, demanding to join the club. How will Takezou be able to keep his club alive and deal with this rascal of a new member?

Outside the magical barriers lies a world overrun by fiery beasts known as Flame Demons, and the only ones who can protect humanity are the Fire Hunters. In the dark woods where the beasts roam is where Touko, a young villager, is rescued from attack by one of these skilled trackers, Koushi. But their meeting was no accident, and a new destiny begins.

Spurred by the flame raging in his heart, the Black Swordsman Guts continues his seemingly endless quest for revenge. Standing in his path are heinous outlaws, delusional evil spirits, and a devout child of god. Even as it chips away at his life, Guts continues to fight his enemies, who wield repulsive and inhumane power, with nary but his body and sword—his strength as a human.

Many centuries ago, man's Armageddon gave birth to the vampires' wrath. As man and immortal clash, a reality-shattering threat looms. Hope resides solely in a new breed of hunter operating under the Vatican's authority. The true battle between holiness and evil has begun.

Avid bookworm and college student Motosu Urano ends up dying in an unforeseen accident. This came right after the news that she would finally be able to work as a librarian as she had always dreamed of. When she regained consciousness, she was reborn as Main, the daughter of a poor soldier. She was in the town of Ehrenfest, which had a harsh class system. But as long as she had books, she didn't really need anything else. However, books were scarce and belonged only to the nobles. But that doesn't stop her, so she makes a decision... "If there aren't any books, I'll just create some."

During the early 1930s in Chicago, the transcontinental train, Flying Pussyfoot, is starting its legendary journey that will leave a trail of blood all over the country. At the same time in New York, the ambitious scientist Szilard and his unwilling aide Ennis are looking for missing bottles of the immortality elixir. In addition, a war between the mafia groups is getting worse. On board the Advena Avis, in 1711, alchemists are about to learn the price of immortality. Takes place in the same universe as Durarara (2010).

The Magic User’s Club is a group of five well-meaning misfits who do more than card tricks – they can use actual magic. And with that magic, they managed to defeat a giant ship from outer space! But their close encounter left an enormous cherry blossom tree right in the middle of the city. It’s so big that it blocks out the sun!

Takeo Takakura, the club's noble (but perverted) president, calls a special Sunday meeting to take care of the tree. It seems simple enough, but when magic is involved, nothing ever goes according to plan…

Paris, 1742. While investigating the murder of his beautiful sister—Lia—D’Eon uncovers an evil which casts shadows in both the palaces of kings and the dark alleys of Europe. It is a dark and strange power—one which allows Lia’s soul to return from beyond and possess her brother in order to avenge her own death.

Belle Lablac doesn’t really fit in as the only human being in a world full of anthropomorphic animals. No fangs, no fur, no scales, no claws. Lonely and eager to discover where she comes from, Belle journeys to find answers to the questions of her heart. Carrying nothing but her giant sword, the Runding, she faces a world of possibilities and pitfalls in hopes of discovering the truth.

Louie, a brawny student at the mage's guild, is reluctantly accepted by three girls (Merrill-thief, Genie-fighter, and Melissa-priestess) as a companion for their adventuring party. As the foursome explore ruins, battle dark creatures, and make new friends, they also uncover a sinister plot within the kingdom.

Musashino, Tokyo. An elementary schooler repeatedly attacks people in the streets. Known only to the public as "Lil Slugger", none of the victims can recall the young boy's face and only three distinct details are left in their memories: golden inline skates, a baseball cap, and the weapon: a bent golden baseball bat. Detectives Ikari and Maniwa set out to track down the perpetrator and put an end to his crimes.

Yuri Ishikawa and her team try to crack unresolved cold cases in Kanagawa Prefecture, Japan.

Life can crush your dreams. Oji is a middle-management drone whose only grip on sanity, in the drudgery of his corporate lifestyle, are the few shreds of hope surrounding his past life as the amazing guitarist of Black Heaven, a heavy metal band that almost made it. In his bleakest moment, the magic of performing is restored to him when a beautiful mysterious woman informs him that only his special sound can save the universe from an evil alien invasion. HARD ROCK SAVES SPACE!?

Mamoru has a far-from-normal high school life with girlfriend Ayako, who possess magical powers.

Aya Mikage and her twin brother Aki are soon driven apart by the forces of fate…

On their sixteenth birthday, Aya and Aki are called to the family home to be given a special present. What they thought was a birthday party, however, was really a test—one which Aya failed. She was found to possess the reincarnated spirit of an ageless celestial maiden (tennyo), one bent on the recovery of her heavenly raiment (hagoromo) and the destruction of the Mikage family. Aya quickly finds herself separated from her beloved brother, and hunted by her own family.