Tensions run high in Holby as foot-ball fans gather for the Saturday match. For Kevin, a rookie policeman, the simple arrest of a drunk biker has tragic consequences. Meanwhile, a disabled young girl poses a challenge for new nurse Jude. The arrested biker arrives at Holby with symptoms of being drunk but tests reveal he has a brain tumour of which he dies of later. A disabled young girl confides to Jude that she has a sexual relationship unknown to her mother. Dr Eddie Gordon and Nurse Kate Wilson disagree over involving Social Services with an asthmatic mother and her home alone daughter.

Mike's dreading spending Christmas alone, but after Rachel's invitation, he might not have to. Meanwhile, the festivities give Charlie and Ash a chance to show some goodwill towards each other. But tidings of comfort and joy are absent for a girl who's brought in to casualty after being violently sick by a railway line. Has she just had too much to drink, or is it something more serious. The shift starts off badly with the death of two young boys and the death of a policeman causes heartbreak for his wife and lover. Two young girls arrive and the staff have to deal with their problems. One of them is pregnant and the other has an eating disorder, leaving both sets of parents are shocked.