Lies between a father and son may prevent House and his team from saving their patient.

While en route to his father's funeral, House must help the team with a differential diagnosis on a young Chinese girl who has collapsed under mysterious circumstances.

A successful, independent blind man is struck down with a mysterious illness, just prior to him asking for his girlfriend's hand in marriage. Meanwhile, House has a family member visit to inform him of a life change. "Love Is Blind" is the fourteenth episode of season eight of House and the 169th overall. The episode debuted in Canada on Global on February 27, 2012, and aired three weeks later in the United States on Fox on March 19, 2012. The unusual three-week delay was a byproduct of the 2012 Daytona 500 rain delay of 30 hours.

Facing a 6-month jail term, and the realization that he won't be there for Wilson at the end, House finds himself examining his entire life while contemplating a dismal future without his best friend.