Brilliant physicist roommates Leonard and Sheldon meet their new neighbor Penny, who begins showing them that as much as they know about science, they know little about actual living.

Leonard volunteers to sign for a package in an attempt to make a good impression on Penny, but when he enlists Sheldon for help, his attempt at chivalry goes terribly awry.

Leonard asks a woman out after he finds out that Penny is seeing someone.

Sheldon's getting fired forces him to explore what life has to offer outside physics, leaving Leonard to take drastic action to snap his friend out of his funk.

Fearing he's wasting his time on Penny, Leonard ends up making a connection with Leslie.

Penny hosts a Halloween party, putting Leonard, Sheldon, Wolowitz, and Koothrappali through a new test of their social skills.

With Wolowitz AWOL with one of her friends, Penny's recruited to fill in for him on the guys' Halo team

Raj's parents set him up on a blind date, but just when he discovers he can talk to her, she shows interest in Sheldon.

When they're invited to present at a physics conference, Sheldon's reluctance to share the credit leads to a tiff between him and Leonard, and Penny's intervention only exacerbates the situation.

Leonard and Sheldon each lie to avoid seeing Penny's concert, but Sheldon's is a bit too complicated for his own good.

With his friends knowing how sour he acts when sick—and avoiding him as a result—Sheldon is nursed by Penny, who hasn't a clue what she's in for.

With Sheldon rattled over meeting Dennis, a 15-year-old physicist who's smarter than he, Leonard helps him look for a way to debunk Dennis's research.

Sheldon finds himself booted from the gang's Physics Bowl team and replaced with Leslie, so he forms his own team, hoping to prove he's superior.

When delivery of another collectible leads to Penny's lashing out at Leonard, he decides it's time to give up his habit, much to his friends' protestation.

The rest of the gang fall for Sheldon's twin sister, and Leonard's plan to win her heart is derailed when Sheldon declares he'll be the one to decide who can date her.

Penny wants to throw a surprise party for Leonard, but Sheldon's indulgence at an electronics store throws her off-track.

Penny's break-up spurs Leonard to summon the courage to ask her out, and each goes to Sheldon for advice on their upcoming date.

Penny's first date with Leonard goes awry; Penny finds Sheldon to be an unwilling confidant.

A jealous Leonard reacts to Penny's new guy by rebounding with Leslie.

Sheldon creates a monster when he introduces Penny to online gaming.

Raj gets an inflated ego and makes a play for Penny after being referenced in a magazine article.

Leonard and his friends stage an intervention to force Sheldon to face his fear of driving.

Sheldon and the gang are confused when a young grad student is attracted to him.

When Sheldon bans Penny from the apartment for numerous minor infractions, she decides to retaliate.

Leonard inadvertently steals away the new woman Wolowitz thinks is the love of his life.

Sheldon is thrilled when Leonard starts dating a woman who meets Sheldon's stringent standards.

Leonard asks Penny for advice when his new relationship starts moving too fast.

Penny starts dating Leonard's handsome colleague; Leonard and his friends are tortured by Sheldon's obsession with gift-giving etiquette.

Penny's criticism of Wolowitz's romantic life pushes him into depression and AWOL for a fighting robot battle the rest of guys are depending on him for.

Sheldon creates a scientific procedure for making friends.

Sheldon's solution to Penny's financial difficulty leads to a confrontation between Leonard and Penny's ex-boyfriend.

Leonard and Penny are drawn together after a disastrous visit from Leonard's mother.

A paintball game leads to a fight between Sheldon and Penny, and romance for Leslie and Wolowitz.

Leonard, Sheldon and Wolowitz are ecstatic to learn that a famous science-fiction actress (Summer Glau) is on board the train they are taking to San Francisco.

Penny's home business turns into a complete nightmare when Sheldon takes over.

Penny squares off with a new beautiful female neighbor who may become the building's "new Penny."

A fellow comic book enthusiast's hitting on Penny leads to Leonard and Howard going to a bar's Ladies' Night.

Leonard and Koothrappali escort a heartbroken Wolowitz to Las Vegas, and Sheldon becomes locked out of his apartment and must stay with Penny.

Penny's second date with Stuart sees her making a comment that gives Leonard new hope for a relationship with her. Wolowitz realizes there's a crucial error in a NASA project he's working on.

The guys' plan to work over the summer at the North Pole makes Penny revaluate her feelings for Leonard.

When Sheldon learns the guys tampered with his expedition data he got from the arctic, he leaves to Texas in disgrace. This results in the guys following him, which threatens Leonard's hope for some romantic time with Penny and the guys' friendship with Sheldon.

Leonard and Penny struggle to recover from an awkward first hookup while Sheldon and Howard stake their best comic books on a bet to determine the species of a cricket.

Howard and Raj visit a Goth nightclub to pick up women while Sheldon attempts to build a better Penny using chocolate-based behavior modification.

Raj must find a new job or be sent back to India, but Sheldon has a solution, which leaves Leonard and Penny dealing with Howard as a third wheel.

After overhearing that Wil Wheaton is entering a trading-card competition, Sheldon decides to enter it himself. Meanwhile, Penny sets up one of her friends on a date with Wolowitz.

Sheldon becomes Leonard's teacher in order to understand football, while an incident with flying a kite threatens Howard and Raj's friendship.

A squabble between Leonard and Penny sees Sheldon playing mediator, though out of his own incovenience from the sitiation rather than altruism.

With Leonard, Howard and Raj away camping in the desert, an injured Penny has only Sheldon to rely on.

After he's humiliated on National Public Radio, Sheldon vows to destroy Kripke, while Wolowitz tries not to destroy his new relationship with Bernadette.

Penny gets help from Sheldon in order to understand what Leonard's work is, while Wolowitz develops a jealousy when Leonard starts hanging out with his new girlfriend.

A Christmas visit from his mother has Leonard discovering she's kept a lot of news from him that she shares with Sheldon and worrying if she'll approve of his romance with Penny.

Leonard is aghast to find out a secret of Penny's: she believes in psychics. Meanwhile, Sheldon tries to assist Koothrappali in picking up a girl at a university mixer.

When their apartment is robbed, Leonard and Sheldon turn to their friends to create a state-of-the-art security system.

Sheldon's search for the answer to a physics problem leads him to work at the Cheesecake Factory with Penny.

Leonard can only bring one guest on a trip to see CERN's Large Hadron Collider (the world's largest and highest energy particle accelerator) in Switzerland on Valentine's Day.

Sheldon winds up in traffic court when he gets a ticket because of Penny.

When the guys find a ring from "The Lord of the Rings" at a garage sale, it threatens to tear them apart.

Sheldon's friends come to his aid when his fear of public speaking stands between him and a coveted award.

A fight between Leonard and Penny threatens their relationship, while Sheldon battles Wil Wheaton in bowling.

When Leonard and Penny aren't speaking, Sheldon goes to extremes to keep them both happy.

Leonard and Sheldon compete for the attention of a famous female physicist.

Leonard tells Penny about how he met Sheldon for the first time...and what happened to the elevator.

While Penny worries that dating Leonard has ruined her for normal guys, Wolowitz and Koothrappali search for Sheldon's perfect match online.

Penny tags along on Sheldon's first ever date; Wolowitz finds a new use for a robotic arm.

Realizing he will not live long enough to download his consciousness into a robot body, Sheldon tries to extend his life span.

The guys are concerned as Sheldon searches for an alternative to human companionship.

An embarrassing secret of Wolowitz's comes to light, while Sheldon and Raj have a small war at work.

Leonard realizes he’s the only one without a girlfriend, while Sheldon wants to get rid of his.

Leonard keeps an affair a secret from Sheldon, Howard and Raj.

Sheldon's answers during an FBI interview put Wolowitz's security clearance in jeopardy.

While the guys camp in line for a long-awaited movie screening, Penny and Bernadette invite Amy to her first slumber party.

Penny asks Leonard to lie to her father, while Howard, Raj and Bernadette pull an all-nighter at a telescope.

Amy finds she has sexual feelings for Penny's ex, while Koothrappali and Wolowitz try to prove who would be the better superhero.

The guys find a "super" use for Penny's new boyfriend, Zack, when they enter a costume contest as the Justice League.

Leonard's idea for a smartphone app derails his friendship with Sheldon.

Bernadette runs into her ex-boyfriend while attending a science event with Wolowitz.

Hoping it will make him a better teacher, Sheldon has Penny give him acting lessons. Raj has fantasies about a friend's girlfriend.

A wealthy donor to the university makes Leonard consider how far he's willing to go for the sake of science.

As Wolowitz contemplates taking things with Bernadette to the next level, Leonard rekindles his relationship with Raj's sister.

Sheldon becomes concerned when everybody begins to hang out at Raj's apartment and discovers Leonard is the center of the group.

Sheldon is baffled by Wolowitz's magic trick. Meanwhile, Leonard realizes dating Priya may make it impossible to continue being friends with Penny.

Sheldon's online-game account is hacked by Todd Zarnecki, who then proceeds to steal all his items prompting the guys to go on a quest to retrieve them. Penny, Bernadette and Amy discuss how Penny groomed Leonard to be willing to try various things and more adventurous boyfriend... for some other woman — Priya.

Sheldon and Amy decide to start several rumors about the others as a test. Meanwhile, Howard takes his relationship with Bernadette to even higher level.

When Leonard spends too much time in the shower with Priya, Sheldon charges Leonard with two violations of the roommate agreement. However, before he can get too far, Priya uses her skills as a lawyer to nullify the charges due to the agreement's vague wording, much to Sheldon's dismay. When the guys take advantage of Priya's skills in order to eat Greek food on pizza night, Sheldon goes to Penny, who invites him to a girls' night out with Amy and Bernadette, which Sheldon agrees to after Penny mentions that they may be talking trash about Priya. After the girls drink some cocktails, they decide to take Sheldon dancing, which Sheldon reluctantly goes along with. After dancing, Sheldon takes an intoxicated Amy back to her apartment and as well as talking about Priya, meets a monkey who is addicted to smoking cigarettes. Amy tells Sheldon not to give in to Priya's law skills, before kissing him and going to her bathroom to vomit.

Raj attempts to cure his social anxiety disorder while Penny uses Bernadette to spy on Leonard and his girlfriend.

When Howard finally breaks the news to his mom that he's engaged to Bernadette, it lands her in the hospital.

When Bernadette receives her PhD, Wolowitz feels emasculated. Raj and Leonard swap places and Penny does something she's regrets.

Penny is worried with how damaged her friendship with the guys will be in the aftermath of her sleeping with Raj while Sheldon becomes the leader of the paintball team.

A fight between Sheldon and Penny leaves Amy caught in the middle, while Leonard tries to spice up his long-distance relationship with Priya.

Leonard and Amy get to know each other better, while Howard and Bernadette spend the weekend with Mrs. Wolowitz.

Penny plays Matchmaker for Raj, which results in him finding a girl he is comfortable talking to.

Sheldon and Leonard get invited to a party at Wil Wheaton's house, and Howard gets an out-of-this-world opportunity.

Sheldon's mother, Mary Cooper, comes to visit, but Sheldon is annoyed that she also spends time with the rest of the gang, instead of catering to his every demand.

A cute comic book artist puts Leonard and Priya’s relationship to the test, while Sheldon tries to scare the guys for Halloween.

Amy becomes heartbroken when she discovers that Penny and Bernadette went wedding dress shopping without her.

Leonard and Penny try hanging out as friends on a 'non-date', but end up purposely ruining each others chances with perspective dates. Meanwhile, Sheldon enlists the help of Bernadette and Amy to overcome his fear of birds.

When Stuart asks Amy out on a date, Sheldon must confront his feelings and consider where his relationship with Amy is going.

Leonard must face his fears after being contacted by his high school tormentor.

Sheldon gets in trouble with Amy when he isn't impressed by her recent accomplishment, and Howard must come to grips with Bernadette's dislike of children.

Leonard, who broke up with Priya, asks Penny out to a spur-of the-moment romantic dinner for two, and the duo contemplates on their relationship.

Leonard and Penny deal with the idea of starting a relationship again and Raj finally finds a "woman" he can talk to without being drunk, in the form of Siri on his new phone. Meanwhile, Sheldon decides to start a YouTube series entitled "Sheldon Cooper presents Fun with Flags" with the help of Amy.

Sheldon's selfish demands force Leonard to reconsider their friendship. Meanwhile, Wolowitz tries to pick his astronaut nickname.

When Sheldon is forced to take his vacation, he goes to work with Amy in her neurobiology lab.

Sheldon battles Kripke for a coveted office at the university. Penny receives a very unusual gift from Amy.

Sheldon becomes agitated when his regular barber is out sick. Astronaut training causes Howard to reconsider wanting to go into space. Penny beats Leonard in chess, the first time she plays.

Sheldon must choose between joining Amy at her aunt's birthday party or playing videogames all weekend with the guys.

Penny buys Leonard and Sheldon “Star Trek” collectibles as a thank-you, leading Sheldon to be haunted by Mr. Spock. Meanwhile, Raj decides he has met the “Future Mrs. Koothrappali” after his parents set him up on a date.

When Wolowitz gets to work with Stephen Hawking, Sheldon is willing to do anything to meet his hero.

After the guys throw Howard a bachelor party, Bernadette reconsiders marrying him after learning about his sexual history.

When NASA moves up Howard's mission, he must face his fears and Bernadette's dad, thus putting the wedding plans in jeopardy. Meanwhile, Leonard says something surprising to Penny in the bedroom.

The fifth season ends with Howard and Bernadette deciding to get married before his NASA mission, causing the gang to scurry into overdrive in an effort to stage the wedding. NASA astronaut Mike Massimino has a cameo as himself.

With his friends on dates, Raj must face his loneliness. Also, Wolowitz is caught in an argument between Bernadette and his mom, even while he’s in space.

When Sheldon learns that Penny is thinking about breaking up with Leonard, he tries to intervene. Meanwhile, in space, the other astronauts pick on Howard.

Amy feels threatened when Sheldon hires a young female assistant, and the pressure of being in space takes its toll on Wolowitz.

When Wolowitz returns from space, he doesn’t get the hero’s welcome he expected. Meanwhile, Game Night turns into a battle of the sexes.

The gang celebrates Halloween at Stuart’s comic book store. Meanwhile, Leonard seduces Penny with science.

Sheldon’s relationship with Stephen Hawking is threatened over a game of “Words with Friends,” and Penny secretly enrolls in a class at the local college.

Wolowitz struggles with moving out of his mother’s house. Meanwhile, Sheldon is caught in the middle of an argument between Amy and Wil Wheaton.

Raj and Howard try to to figure out why Sheldon disappears at 2:45 every afternoon; jealousy arises in Penny and Leonard's relationship.

When the University reassigns Sheldon’s parking spot to Wolowitz, their fight affects the whole gang.

When Amy gets sick, Sheldon tries to nurse her back to health; Wolowitz and his father-in-law plan a fishing trip.

During a Dungeons and Dragons game, Sheldon revisits Christmas memories; Amy, Penny and Bernadette look for a date for Raj.

When Sheldon is accused of sexual harassment, he ends up getting Raj, Leonard and Howard in trouble.

As the guys don costumes and go on a road trip to a comic book convention, the ladies decide to stay home and try to interpret a comic book.

Sheldon faces a crisis of confidence when he is forced to work with his nemesis, Barry Kripke; Raj and Howard buy expensive action figures of themselves.

A fight between Sheldon and Leonard impacts Amy and Penny's living arrangements; while Howard is away, Raj helps Mrs. Wolowitz out.

The guys search for a perfect Valentine's Day gift for their significant others; Stuart and Raj host a "lonely people" party at the comic book store.

After a bad date, Koothrappali decides to never leave his apartment; Penny's acting skills impress Sheldon.

Leonard, Sheldon and Howard give lectures on science to junior high students. The girls ditch work to go to Disneyland. Raj devises a date for Lucy that fixes their social anxiety problems.

Howard considers whether or not he should open a letter from his father; Penny and Leonard host a "grown-up" cocktail party.

The girls get involved when Leonard, Sheldon and Raj compete for tenure at the University.

Amy tries to help Sheldon get over his compulsive need for closure when one of his favorite TV shows is canceled; Raj discovers a secret about Lucy.

Leonard and Sheldon hire the host (Bob Newhart) of their favorite childhood TV show to perform; Bernadette and Howard run into trouble while dog-sitting for Raj's pet.

A date between Raj and Lucy takes both of them out of their comfort zones. After a trip to Las Vegas goes awry, the girls join in on a Dungeons and Dragons game, which causes Amy and Sheldon to re-evaluate their relationship.

When Leonard receives an exciting opportunity to work overseas, Penny and Sheldon are thrown for a loop. Raj and Lucy's relationship comes to a crossroad.