A murder scene complete with lots of blood but no victim and high tech life-extension science are all part of the investigation as Castle and Beckett try to solve a murder without a body. Meanwhile, Alexis waits to hear news about her application to Stanford

When Beau Randolf, the founder of hit adult video franchise "College Girls Gone Crazy," is murdered, Castle and Beckett are confronted with a lengthy list of husbands, fathers and ex-college girls who all have motive. So to find the killer, they must delve deep into the victim’s life, where they find surprises at every turn. Also Alexis starts a video blog, but Castle is not happy that personal and intimate details about her life are being made public.