Catherine and Sara deal with the death of what at first seems to be a transvestite. Later during autopsy they find out that the make-up he seemed to be wearing was actually facepaint, he was a clown. Grissom, Nick, and Warrick deal with the death of a man in a homeless area. They found out he worked in a recovery center for drug users.

One night, four cases. Grissom and Brass get a stolen hummer and a taco stand. Warrick gets a dead car show girl. Sara and Greg get a dead bodybuilder. Nick gets a dead boy found on a bench.

The team investigates a girl whose whole family had been killed and she is supposedly possessed by the devil.