The team investigates an underground mob. Warrick ends up becoming the prime suspect in a murder that's related to the mob, and his addiction to pills starts to have a significant impact on his job as a CSI.

The world of illegal dog fighting is explored by Grissom and the rest of the team when they take on the case of a wealthy socialite who was murdered. Meanwhile, Warrick struggles to clear his name in the recent exotic dancer murder case.