When Peter gets a pet parrot, he begins acting like a pirate. Peter accidentally kills the bird after raising hell through all of Quahog. Meanwhile, when Brian is visiting the vet, Chris falls in love with the intern, Anna.

Peter's boss Angela sends him back to the third grade so that he can qualify for a work promotion. Meanwhile, Brian, Frank Sinatra Jr. and Stewie open the coolest club in Quahog.

When Brian begins dating an older woman, the family begins to make fun of him. After Brian's new fling breaks her hip, he gets the pleasure of becoming her errand boy.

When Brian discovers that Carter Pewterschmidt’s pharmaceutical company is withholding the cure for cancer from the public in order to gain more profit, he and Stewie plot to expose the big secret that could change the world. Meanwhile, Quagmire reveals a hair-raising secret of his own.

Peter's friends roast him. With his feelings hurt, he seeks refuge by befriending a group of gossipy women.

Peter, Cleveland and Joe come across a VHS tape called “Winter/Summer” an Asian soap opera that Quagmire starred in when he was living in Korea. Unable to find the final episode of the series, the guys travel to Korea to find it and Quagmire is reunited with his old lover. Meanwhile, Stewie worries he might become a redhead.

Peter gets lost in the mall overnight after his family abandons him. Meanwhile, Brian pretends to be a millionaire to win over a girl.

To everyone’s surprise, Chris wins homecoming king. However, Meg finds out that the cool kids plan to prank him during the homecoming ceremony, so they go to the school to investigate. Meanwhile, Cleveland starts hanging out with Jerome, the bartender. So Peter and the guys try to replace him.

Peter becomes friends with a cool, handsome paramedic named Stryker Foxx. Wrapped up in his newfound "coolness," he soon dumps Quagmire, Joe and Cleveland.

With the brewery under construction, Lois implores Peter to take a new job, but grows irate when he begins work at the grocery store. Meanwhile, armed with his police stories, Joe and Brian team up to write their own true crime novel.