Lois fulfills a lifelong dream of being a model. Stewie starts on a multi-level marketing company. Brian in need of cash to buy his de-worming medication agrees to become his salesman.

Brian's gay cousin Jasper visits the Griffin house and announces that he is engaged to his partner and wants to be married at their house. When Mayor West bans gay marriage in an effort to cover up and bring attention away from a scandal of his own, Brian resorts to hostile actions to try to change the Mayor's mind. Lois and Peter question their view towards gay marriage while Chris joins the "Young Republicans" Club to impress a girl.

Peter needs a new kidney after his energy-drink addiction causes renal failure. Meanwhile, Chris is chosen to introduce United States President Barack Obama at his school after winning an essay contest. Trouble is, Meg wrote the essay.

Chris's search for a new hobby leads him to befriend a puppeteer named Franz, until his checkered past is revealed.

Stewie tries to be a big boy and steals Brian's car for a joy ride but lands in a bit of trouble. Meanwhile, Ryan Reynolds visits Quahog and becomes obsessed with Peter.

Peter and the guys take a stand against their wives and flee to the Deep South on a road trip. On their Deep South road trip, Peter and the guys earn a one-way ticket to jail, then decide to make a run for it.

Brian discovers that his new blind girlfriend can't stand dogs, and Peter cannot negotiate his way down the new staircase.

Overwhelmed with financial troubles, Mort asks Peter and Quagmire to help him save his pharmacy. However, things take a turn for the worse when the trio decides to burn it down to collect insurance money

Peter and Chris go to fat camp where they cross paths with a serial killer who targets overweight kids; an album cover frightens Stewie.

When Peter's favorite kiddie show gets canceled, he decides to create and star in his own. Meanwhile, Meg starts an internship for Dr. Hartman.

Meg's exciting European adventure comes to a halt when she is kidnapped; Stewie and Brian embark on an action-packed rescue mission..

Peter talks Joe into having an affair and gets into another epic fight with the giant chicken.

When Brian discovers that Carter Pewterschmidt’s pharmaceutical company is withholding the cure for cancer from the public in order to gain more profit, he and Stewie plot to expose the big secret that could change the world. Meanwhile, Quagmire reveals a hair-raising secret of his own.

When the criminal who shot Joe years ago, leaving Joe in a wheelchair, becomes a fugitive, Quagmire, Joe and Peter team up to hunt the bad guy down.

When Meg learns her crush is gay and interested in Chris, she uses her brother to get closer to him.

As the Griffin family is preparing for Christmas, Peter tells his own version of the Nativity story.

To boost Chris' self-esteem, Peter and Lois send him to space camp. When camp ends and the Griffins come to pick Chris up, they accidentally are launched into outer space, and it's up to Chris to land the clan safely back on earth.

Brian writes a play that becomes a hit in Quahog, but loses his confidence when he finds that the play Stewie wrote is better than his.

When Peter, Quagmire and Joe visit the Harvard University campus, Quagmire accidentally marries a prostitute. In order to get out of his marriage, Quagmire pretends to be lovers with Peter.

Peter is convinced that a restaurant placemat is a treasure map. Word quickly spreads about the alleged cache, sparking a city-wide search and turning the citizens of Quahog against each other.

When the brewery announces it will be firing one employee, Peter is nervous he will be the one let go; the family departs on a Yacht Rock cruise that doesn't go as expected.

Peter and his friends are sick of forgetting the million-dollar business ideas they come up with while drinking, so they strap on Joe's police body cams to record their every move. Meanwhile, Quagmire is trying to come to terms with an unexpected family development.

When Stewie receives a participation medal in his school's toddler games, he begins to question everything he has ever won. Meanwhile, Peter causes a fight between Lois' parents and must repair the damage he caused.

When Quagmire opens a cat café in town, Brian decides to take a stand to get the café shut down. Meanwhile, when Meg and Chris get in trouble at school, Lois becomes nervous and decides they need to go to church camp in order to find their way.

To celebrate Peter and Lois' wedding anniversary, the Griffins present their own versions of three well-known love stories.

Peter secretly gets a credit card and overspends the family money, so Lois grounds him. To plan the perfect escape, he builds a tunnel leading directly to The Drunken Clam.

When Peter starts coaching for Quahog's minor league baseball team, he gets constipated during the national anthem and must kneel, unintentionally becoming the face of racial justice.

Peter's non-stop sweating becomes a liability at his company, so his boss tells him to work from home. Meanwhile, after Stewie and Chris cause thousands of dollars in damage to an electronics store, the two create a fake Kickstarter campaign with Brian to pay back the money.

Cooped up in a hotel room due to a big storm, the Griffins pass the time by reimagining three stories from the Bible.

Principal Shepherd moves in with the Griffins after he is fired for fat-shaming Chris at school. Meanwhile, Brian sues Stewie for writing a series of children's books which portray him as an idiot.

Stewie finally says his first word, and it's a swear. When Lois is shunned by the other moms, she tries to figure out where Stewie could have possibly learned it.

Peter and Lois accidentally set up a cutaway gag together, which somehow transports them into the cutaway itself.

Brian's new job as a journalist leads him to uncover that Pawtucket Pat, Quahog's hero and brewery founder, took part in racist actions against Native Americans. The town becomes divided on whether or not to remove the statue that commemorates him.

Meg agrees to be Bruce and Jeffery’s surrogate causing a pregnant Meg to annoy her family. But, when the couple fails to pick up the baby, the Griffins must take care of their new family.

Peter and Lois vacation in Florida, only to discover they've rented a condo in a retirement community. Back at home, Brian helps Stewie take his first shower.

Stewie tries to civilize his half-brother, Boston Stewie, so that he may be adopted. Meanwhile, Meg and Chris start a venture in which people online pay Chris to sit on and smash cupcakes.

Lois decides to sell the family's television to help pay for Christmas presents, but when Kevin James gets upset over losing Peter as a viewer, he apparates into the Griffin house.