On a historic night where Jimmy Kimmel has previously debuted such pieces as the I'm F@#%-ing Ben Affleck music video and Mel Gibson's The Colonel, he introduced a new star-studded video including Jimmy and 15 of the most handsome men in Hollywood who come together

for the handsomest gathering ever.

Jimmy also welcomed two-time Academy Award® nominee Robert Downey Jr. who presented the world premiere of the new Iron Man 2 trailer, and a musical performance by Grammy Award® winner Keith Urban. Plus special appearances by Ben Affleck, Jennifer Garner, Matthew McConaughey, Patrick Dempsey, Sting, and many more.

Actor Robert Downey Jr.; actress Ayo Edebiri; Fridayy performs.

Actors Cillian Murphy, Emily Blunt and Robert Downey Jr. ("Oppenheimer"); comic Rory Scovel.