Melinda Gordon just got married; during the dinner she sees something being drawn on the window and she knows it's a ghost. But for the first time, the ghost comes inside her house and that unsettles her. Despite being afraid, she tries to help him reunite with his family and pass along the message he needs her to say.

A man killed in a biking accident seeks Melinda's help to save his fiance's life and finding out who received his heart afterwards.

Melinda experiences a sense of dread when she realizes that a plane is going to crash when the spirits of the pilot and flight attendant contact her.

After a jetliner crashes Melinda faces the overwhelming task of helping hundreds of passengers crossover. While Melinda faces this task she finds that the “Wide Brim Man” is working against her. Melinda must also try to work with the crash investigators who are trying to find out how Melinda knew that the plane was going to crash.

Melinda worries that Andrea is being influenced not to cross over. Melinda seeks the help of an expert in history and the occult in helping to identify the wide brimmed hat man.

A rock and roll enthusiast expands his love to living teens by tormenting them into stealing. Melinda must also deal with the ghost of her scheming ex-boyfriend.

Five accidents, and four signs, something else is going to happen. Melinda becomes concerned for the safety of the people she loves when a ghost prophet shows her visions of the future. The fellow Ghost Whisperer, who Melinda doesn't trust is still in Grandview.

Melinda visits the Mayor of Grandview and asks him to cancel the memorial dedication they are holding. She speaks to the ghost of a mail person and is looking for a young girl named Kristen. Later, Melinda and Professor Payne search for missing children after their Nanny says that they left with a man named Gabriel. Meanwhile, a mysterious man tries to get Melinda to stop helping the good guys.

Jennifer goes to Melinda’s store to sell some belongings that came from her deceased parent’s house. Melinda then helps Jennifer with her father who died when she was only a toddler. Someone takes photos of Melinda and they show something suspicious. Melinda finds that she has a hidden connection to Grandview while digging into her families past.

Melinda discovers the truth about her family's past through a series of bodily possessions.

While facing dramatic personal changes, Melinda struggles to help a desperate teenage ghost, feeling her gift of being able to talk to the dead is no longer helpful.

Jim and Melinda's wedding is overtaken by an ambitious wedding planner while Melinda deals with dreams that seem to threaten her child. Elsewhere, Eli's ex, Zoe, is caught up in a book sale with tragic consequences.

Melinda helps a dead doctor who is reliving a surgery that went wrong.

A ghost who knows of a hidden munitions dump with unexploded bombs confides in Melinda that one of those bombs is missing and in the wrong hands

Jim's hospital is being haunted by the ghosts of kids from an abandoned polio ward in the early 1900’s. And the connection of Aidan, Melinda, the Shinies and the Shadows will come to a climax and Melinda and Jim will realize that they know almost nothing about Aiden's powers.