Horatio is driven to find his brother's killer and protect the niece he never knew existed when a woman shows up with Ray's illegitimate child. The team explores a voyeuristic Internet site in connection with a stockbroker's murder.

Horatio's life is changed forever when he learns important information about his deceased brother. Horatio must now figure out what to do with this information about his brother, Raymond, and whether or not to tell Yelina. Meanwhile, the team investigates when a woman is murdered at a crowded bar after she's approached by a female employee of a service that helps men pick-up women. Also, when Delko loses his badge after some reckless behavior and it's used in a crime, he must locate the badge before it's used again.

A former high school football star is murdered at a reunion, the CSIs must find the killer. The victim was the big man on campus in high school and there are a lot of guests at the reunion with reasons to resent him all these years. Now, the team must investigate everyone, from the head cheerleader to the school misfit, to see who held a decade-old grudge big enough to kill. Meanwhile, Horatio and Delko arrive at a crime scene and discover that it's already been processed, leading Horatio to uncover further information about his brother possibly being alive.