When a priest is found dead in his rectory after being brutally shot, Megan, Calleigh and Speedle must untangle a messy web of familial issues that lead to his death. Elsewhere, Horatio and Eric attempt to solve the emotional case of an exploded vehicle, which was home to a mother with child.

During a typical morning rush hour in downtown Miami, an unseen sniper chooses three victims at random and opens fire, killing each with a single shot to the head. Horatio and his crew rush to the scene, which is quickly mobbed by TV news reporters eager to spin the murders into a national story. The initial investigation doesn't reveal much, as there were no witnesses and little evidence remains. But the case heats up when the sniper strikes again, killing two more innocent people.

A nude man is found tied to his bed, having suffocated on a rag stuffed in his mouth while he was being sexually assaulted. Meanwhile, while investigating the murder of a crematorium owner, the CSIs discover dozens of bodies that were never cremated.