Bernie is booked on a popular morning radio show, and he gets himself into trouble with the whole family when he draws from his private life to bring comedy to the public airwaves.

After taking the kids to the movies, Las Vegas-bound Bernie is further delayed by scenes that grow out of what they saw there, but weren't supposed to see.

Wanda's parents, Lloyd and Leora, visit the Mac household. Bernie and Wanda first think the visit will be good for the kids. But Lloyd and Leora start to give them more then they bargained for when hey start to criticize Bernie and Wanda's parenting skills. Bernie and Wanda decide to let the grandparents take care of the kids and leave for several hours. When they return, Bernie and Wanda tell Lloyd and Leora how they feel and decide the best thing is for the grandparents to leave. When Vanessa finds out, she is very upset because Leora did not tell her parents that a boy kissed her. Everyone makes up and decide to leave parenting to Bernie and Wanda.

When Bernie lands the dramatic lead role of a stroke afflicted former track star, he has a hard time convincing everyone he has the chops to be a serious dramatic actor and reaches out to Angela Bassett for acting advice. Since Bernie is working and cannot care for the kids after school, Wanda must put the younger kids into daycare at her work. Upset at being stuck with a bunch of babies, Jordan leads a child rebellion where the kids escape daycare and wreak havoc on the office. Meanwhile, Vanessa pretends to be poor, so that Teri, a girl at school, will like her. But the plan backfires when Teri finds out that Vanessa is lying and that she is really Bernie Mac's niece.

When Wanda quits her job after getting passed up for a promotion, she tries to re-channel her energies toward Bernie. The togetherness starts to wear thin, however, when she upsets Bernie's writing process as he prepares for his talk show appearance on "The Ellen DeGeneres Show." Meanwhile, Jordan wants to become friends with the big boys on the block, and figures the best way to do it is to hook one of them up with his older sister, Vanessa.

Wanda decides to enroll the kids in an organization that teaches social skills to young people, with Vanessa instantly making new friends, who manage to get themselves into trouble & in mall jail.

Upset that Vanessa is living the free life, Bernie Mac has Vanessa work for him. Shortly, after wards Vanessa learns that his co-workers get all this free stuff because they mention they work for Bernie Mac. Vanessa takes big advantage of this, until Bernie Mac finds out. Later on, Vanessa has to bring one of his precious statues home but it breaks in a car accident. Jordan offers to fix it, with of course a price (some of the free stuff Vanessa got).

Jordan turns 13, but still acts like a monster fighting with Bryana. Eventually Jordan lets Bryana walk all over him to avoid further punishment. When he gets his gifts back, Bernie holds back an R-rated movie. Later when Bernie asks Jordan to babysit Bryana one night, Jordan accepts just so he can watch the R-rated movie behind his back.

Jordan and Bernie Mac start a fantasy football league but do poor; and Bernie Mac won't really listen to Jordan. With that, Jordan eventually goes to a different league secretly behind Bernie Mac's back. Vanessa primps herself up with make-up for her senior photo. Bryana wants some of the make up too, so Vanessa gives her some of her old makeup. But Bryana gets caught with it at school.

Vanessa's school prom is coming up so Bernie Mac picks a boy friend out for her (after doing his usual protective background check). Even after he chooses, he has all these worried fantasies. Bryana injures her ankle so Jordan has to be her servant, but in the end after Bryana took it a bit far Jordan gets some redemption.

Jordan dates Erica, one of the cheerleaders at school. Bernie is delighted, but when Jordan and Erica break up, he tries to remedy the situation.