Victims of a bus accident are treated; two doctors join the rotation; O'Hara is happy spending time with her son; Akalitus gives Eddie his job back.

Kevin demands full custody. A bus crash patient returns after contracting sepsis. Coop threatens to quit.

After their custody meeting, Jackie rear-ends Kevin and wakes up as a patient in her own ER. Kevin accuses her of using. Coop begins covering for Carrie and taking on a lot more work. When Carrie checks on Jackie, she writes her a prescription for Oxy, unaware she's an addict. The most unlikely person asks Jackie out on a date.

A heavily medicated Jane Doe is brought into the ER and Jackie tasks Zoey with finding out who she is. Coop invites Carrie to dinner. Jackie faces conflict with both her daughters - Fiona has been acting out in class while Grace sneaks around the city with her older boyfriend.

Jackie is nervous about her date with Frank, so Zoey and Thor help her get ready and Eddie offers some friendly pointers. Prentiss misdiagnoses an injured dancer, but Akalitus and Coop catch his mistake before the patient leaves. Mike Cruz calls Jackie in a moment of need.

Jackie and Grace recover from their nights of indiscretion; Carrie uses flashcards to strengthen her skills.

Akalitus forgets to hire an escort for a psych patient who then lays waste to the pharmacy; Frank cancels a lunch date with Jackie; Zoey hears Coop and Carrie having sex; Jackie worries about Frank when she learns that a cop has been shot.

Kevin interrupts Jackie and Frank's night. Akalitus' blood results are in and her memory loss is a result of a medication she's been taking. Zoey helps Prentiss organize his disaster of an office. Meanwhile, Jackie is convinced that Grace is sneaking behind her back to see Danny, but Grace assures her they broke up. Frank urges Jackie to work on her issues - so she attends an AA meeting.

Jackie and Frank have sex for the first time and he tells her he loves her. Akalitus has an extra spring in her step. Coop wants to take his mentoring of Carrie to the next level. Kevin and Grace show up at the hospital after Kevin finds a bag of pills in Grace's bag.

It's Jackie's one year anniversary of sobriety and she and Frank fight about their relationship. Zoey acts very professional and rigid around Prentiss after their intimate evening. Carrie's peer review does not go well. Grace has a breakdown about Jackie. Jackie takes something she shouldn't have.

Jackie's back to using again, but she's doing it differently this time: maintaining a clean and sober cover, going to 12-step meetings - even finding herself a sponsor - all the while getting her drugs from the towel girl at the gym. Meanwhile at All Saints, Zoey finds out that everyone knows about her 'secret' relationship with Prentiss. Season premiere.

Jackie steals Dr. Roman's DEA number. Coop is recruited by a 'sperm scout.'

Coop learns his sperm count is too low for donation; Carrie gets a lucky break; Akalitus' poker habit pays off; Grace drops a bomb on Jackie.

Jackie goes off the deep end; Frank discloses a secret about his past.

Frank searches Jackie's house for drugs, but she removes them in time and hides her stash in a ladies room at the hospital. Later, Jackie bonds with a homeless, alcoholic nun; and finds comfort in the arms of a fellow drug user. Meanwhile, Zoey confronts Prentiss about his dissatisfaction and encourages him to do what he loves.

Jackie's fake identity is compromised when it's learned that Carrie's DEA number has been stolen by a woman named Nancy Wood. Meanwhile, Jackie worries about her dwindling bank account and lack of pills; and Prentiss gives Zoey a shocking message.

Jackie is ambushed by Antoinette. Coop's dream finally comes true.

Jackie detoxes at home - with help. Frank raises an objection about Grace.

Jackie learns about a DEA investigation at the hospital that will require her to take a urine test, so she plots to get around it. Meanwhile, Kevin and Mia plan their wedding; the homeless nun returns in worse shape than ever; and Coop and Carrie find a way to skirt their no sex in the hospital rule.

Jackie breaks up with Frank and tries to separate herself from the people closest to her so she can keep using drugs. Meanwhile, Carrie forgets Coop's 40th birthday; the DEA investigation intensifies; and Zoey decides to become a nurse practitioner.

Jackie reluctantly attends Kevin's wedding. Carrie makes demands on Coop.

Coop gets a surprise. Jackie hits the road. Season finale.

Picking up with her arrest, Jackie suffers through detox.

Jackie gets inventive, setting her sights on returning to All Saints.

Jackie's back at All Saints - but back to square one in a new role.

Still strapped for cash, Jackie's dealing takes a surprising turn.

Jackie stirs up trouble for the developers. Coop preps for his last day.

Zoey leads the ER nurses on a walkout. Jackie battles her cravings.

Jackie and Eddie make a purge their stash. Dr. Prince and Akalitus bond.

Dr. Prince enlists Jackie's help with a patient. Thor reveals a secret.

Zoey finally confronts Jackie. Dr. Prince attracts a mob to All Saints.

An unexpected knock at the door puts Jackie and Eddie in jeopardy.

Jackie is forced to perform a procedure on her own. Zoey learns a secret.

Jackie gets offered a job - and wants Zoey to come with her. Series finale.