Stardate: 48315.6. While in pursuit of a Maquis ship in a region of space known as the 'Badlands', Captain Kathryn Janeway and her crew aboard Voyager and the Maquis ship are transported 70,000 light years from home into the uncharted region of the galaxy known as the Delta Quadrant.

Stardate: 48579.4. The discovery of a wormhole leading to the Alpha Quadrant elates the crew, however, their only contact within range is a skeptical and paranoid Romulan.

Stardate: 48975.1. After discovering a 1936 Ford truck from Earth floating in space Voyager discovers a series of cryo-statis chambers containing abductees from Earth during the 1930's, including Amelia Earhart and her navigator.

Stardate: Unknown. Captain Janeway starts seeing characters and objects from her holo-novel around the ship. Soon afterwards the crew begins entering a catatonic state one by one, while only Kes and the Doctor remain unaffected.

Stardate: Unknown. Janeway tries to make an alliance with a Kazon sect for their own protection and so they can continue their journey through the Delta Quadrant.

Stardate: 49485.2. After weeks of erratic behavior, Tom Paris leaves Voyager and joins a Talaxian convoy.

Stardate: 49690.1. When Captain Janeway and Chakotay contract an incurable virus they are left on a planet that shield them from its effects. While Janeway searches for a cure, she begins to form a deeper relationship with her first officer. Onboard Voyager, Tuvok, who is now in command, faces a near mutiny.

Stardate: 50518.6. Captain Janeway repeatedly dies after she and Chakotay crash into a planet in what appears to be a time loop. Soon, her deceased father appears and tells her that she is dead and must accept her situation and move on.

Stardate: 50863.2. The Doctor decides he should create a holographic family in order to expand himself. When B'Elanna is disgusted by its unrealistic perfectionism, she alters the program to include random events and outcomes with interesting and devastating results.

Stardate: Unknown. When Voyager is forced to eject its warp core, Torres and Paris take a shuttle to retrieve it. But when the shuttle is damaged, the two officers are forced to abandon it—and find themselves alone in space with a rapidly depleting oxygen supply.

Stardate: 51501.4. As letters from the Alpha Quadrant come trickling through the communications array, the Voyager crew learns of an assortment of joyous, disturbing, and inevitable news.

Stardate: 51929.3. The crew goes into stasis during a month-long journey through a nebula, leaving Seven and the Doctor in sole charge of running the ship.

Stardate: Unknown. A moral dilemma arises when the Doctor is forced to consult the specialized medical database of a Cardassian war criminal in order to save Torres' life.