An 18-year old in need of a double-lung transplant, struggles to survive as the team runs into an obstacle that may prevent her from being eligible for the procedure.

Andy and Sophia treat a car crash victim named Victor dying from ALS who asks to be to taken off of life support so his organs can be used to save others. Meanwhile, David tends to a foster parent with pulmonary hypertension who refuses admission to the hospital.

A firefighter must decide whether to be a living donor to her captain, a man who has mistreated her. Meanwhile, Andy's uncle turns up with a stab wound and asks him not to report the incident for fear it will violate his parole.