Megabyte and Hexadecimal are about to take the core, but Mainframe is saved at the last minute by an incoming game cube. However with Bob gone, Enzo is left having the answer the call of the guardian protocol.

The traps Mouse once placed to stop the web creatures from accessing Mainframe are now making it difficult for the sprites to return home.

Mainframe begins to crash around them and users from games played break out into mainframe. Matrix meets up with an enemy from his past.