In the first episode, Mika welcomes big names in entertainment to his show, such as the master of TV improvisation Renzo Arbore and actors Marco Giallini, Gianmarco Tognazzi and Francesco Montanari. Also entering Casa Mika will be big stars of the national and international music scene, accompanied by the 16-piece resident band directed by Valeriano Chiaravalle: this week, world rock star Sting, LP, Malika Ayane, Francesco Renga and Benji & Fede will be with Mika.

Mika, again, opens the doors of his home together with his special roommate, Sarah Felberbaum and with the extraordinary participation of Virginia Raffaele. Guests of the episode: Monica Bellucci, Luca Zingaretti, Emma, Morgan, Raphael Gualazzi, Michele Bravi and Joan Thiele. Then, a special personal remembrance to Nobel laureate Dario Fo and his visionary and cheerful way of looking at the world. The Banda Rulli Frulli from Finale Emilia (MO), a marching band with as many as seventy members including girls, boys, teenagers and young people, some of whom are differently abled.

Guests of the episode include Rossy De Palma, Pedro Almodóvar's muse, Eros Ramazzotti, Giorgia, Elio and Kendji, Fabio Fazio and Sabrina Impacciatore. Also returning are the positive stories in which music has become an element of salvation, such as that of the Piccola Orchestra di Tor Pignattara (Rome), a multiethnic orchestra founded in 2012 formed by 13- to 18-year-olds, second-generation immigrants and Romans, whose heart is in the working-class neighborhood of Tor Pignattara. A multiethnic orchestra formed in 2012 by boys between 13 and 18 years old, second-generation immigrants and Romans.

Lots of guests for the grand finale of Tonight at Casa Mika: Kylie Minogue, Antonella Clerici, Ornella Muti, Pierfrancesco Favino, Pupo and poet Patrizia Cavalli, Chiara Galiazzo and Jack Savoretti, the Italian Opera Orchestra. A new story in which music changed lives, that of the Papageno Choir of the Dozza Prison in Bologna. This week Mika, in the guise of a taxi driver, will be driving in Catanese traffic surprising customers, but not without some inconvenience.