Jim and Tim decide to take on the duties of the Middleton Mascot and Ron takes it upon himself to train them. Meanwhile, Drakken is broken out of prison by an alien named Warmonga.

High school graduation nears for the senior class, but Warmonga's return jeopardizes everything as Team Possible goes through their toughest odds yet to save the planet.

After both Kim and Drakken have been taken captive, Ron and Shego must race to rescue them from the clutches of Warmonga, Warhok, and the other invaders. All of the main characters must now band together to save the planet that they call home.