The casino has reopened. Ed and Mike work on a case of counterfeit casino chips. Per his accountant's suggestion, Danny must sell his father's house. Later, Danny's accountant is part of a poker game where one of the players is a man who robs one of the casino's guests. Monica Mancuso, the new owner, wants a dealer to be fired because he keeps dealing winning hands to the players.

Danny is with blackjack player Gabe Labrador who's wearing a wig and counting cards. The man doesn't want to stop playing and claims he must win big to pay off the men who kidnapped his daughter. Ed, Mike, Danny and a cop from Metro work on the case even though they aren't sure Gabe is telling the truth. Mary seems to still be helping Danny taking care of his dad's stuff. She is still dating Jake. A player who won a lot of money wants to give it back, but then wants it back, then wants to give it again, etc. Sam and Woody (from "Crossing Jordan") are getting very well acquainted... Jordan from "Crossing Jordan" is also in this episode.

Sam's whale is named Trey Cooper, a handsome 30-year-old who brought his Great Dane to the casino. There are a lot of dogs around the casino as the Nevada State Dog Show is taking place. Jillian enters the Deline's dog in the competition. Monica and Danny meet with an 80-year-old woman named Dottie. Monica offers 3 million for Dottie's house in order to build a golf course. Things will become complicated when on the demolition site, construction workers find a skeleton. A CSI believes it could be the body of Seymour "Blue Jaw" Magoon, a member of a 40s gang called Murder Inc. Mike helps a couple who's "stuck" together. Jake seems to still be in Mary's life. Mike is still helping Danny to find information on the woman his father was dating before he died.

After Ed's doctor warns him that his blood pressure is dangerously high, Ed becoms the victim of identity theft. Sam's half-brother visits. Mike borrows Ed's Aston Martin with unforseen consequences.

Sam's brother is staying longer than expected because he's having an affair with Monica. Danny tracks down the woman who appears on pictures with his father.