Maya checks into the hospital to undergo surgery for the removal of a fibroid tumor. Joan's friends (especially Lynn) question her priorities when she decides to leave Maya's bedside to attend an important business dinner with Sean. Toni continues to clash with Greg over his lack of income. At the hospital, she takes an immediate interest in Maya's doctor, the wealthy and handsome Dr. Clay Spencer.

Sean grows uncomfortable with Joan's relationship with Davis, as he feels that she flirts with him too much. After she confesses that they once shared a kiss, Sean upsets Joan by ordering her to stay away from Davis and 847 for good. Meanwhile, Toni angers Greg by displaying some of his paintings at the restaurant; and Darnell becomes impatient when Maya is reluctant to resume sexual relations with him after her surgery.

Toni cheats on Greg with Clay and winds up contracting chlamydia. Joan frets about the fact that Sean has yet to tell her that he loves her, especially after he reveals that he has been offered a six-month job in New York. She seeks her friends' advice on how to coax a love declaration from him. Meanwhile, Maya feels threatened by the temp who filled in as Joan's assistant during her absence.

After Toni accepts Clay's marriage proposal, a disapproving Joan advises her to look into her heart, as she believes that Greg is the one she really loves. Toni comes to agree with her, and tells Clay that she cannot marry him. Unfortunately, in the meantime, Joan (unaware that Greg and Toni are even still together) accidentally tells Greg that Toni is engaged to another man, prompting him to dump her. Meanwhile, William issues an ultimatum to Yvonne after she is shot in the line of duty; and Maya continues to try to avoid having sex with Darnell.