When a man leaves his home in the morning with his daughter to take her to school and then to open his dry-cleaning store, but they both of they never make it there .

Delia , a television reporter, disappears in the middle of the investigation of a nightclub owner who is a suspected drug dealer. They also discovers that Delia was working on the case of a murderer on death row who she thought was innocent, and who might be linked to an assistant district attorney working with Jack on the case.

When the team tries to plot a strategy after they find out that Samantha has been shot and that she might be critically injured in the hostage crisis situation. Jack makes a deal with Berry so that Sam can get help and Jack goes in there and takes Sam's place.

A school bus is abducted by kidnappers who demand more and more for ransom.

The team searches for a mother and her two children, who are last seen boarding a yacht which is later found adrift in New York's Harbor with only its dead captain aboard. Meanwhile, Malone gets ready to leave the team and move with his family to Chicago.

The team searches for a recently blinded girl and her companion who disappeared during a camping trip. Vivian takes over as the supervisor, while Jack struggles to say goodbye to his family.

When a nanny, and the child she took care of, disappear from her employers' home after being fired by them, the team must determine if the nanny is a kidnapping victim, or a kidnapping suspect.

Things with Jack and Maria's divorce are getting nastier as Maria's attorney forces Jack to relive not only his childhood traumas, but also throw his affair with Sam in his face and attack his dedication to his job.

The team uncovers a history of deception as they search for a man posing as a college student vanishes.

While working on a high profile civil case, a trial consultant vanishes. Jack and Sam learn how to make adjustments as Brian and Finn spend more time together.

After Hanna's boyfriend disappears from Chicago along the way to New York, Jack hesitates to assign the team on his case.

The team searches for a man who goes missing after a late night dive and try to zero in on who could be responsible for his disappearance. Meanwhile, Danny and Elena take their relationship to another level.