A young mother disappears after leaving her three year old son with a babysitter.

Martin is swamped with guilt after a young boy is kidnapped shortly after he jogs by. The team tries to reassure Martin that his presence was a help rather than a hindrance as they search for the kidnapped child, but Sam's continued reluctance to admit to their relationship partnered with Martin's jealousy of her relationship with Jack only cause more problems.

Paige was last seen sneaking out of her office at the same time as an NYPD detective was asking her boss to direct him to Paige for a routine inquiry. To the team's surprise, the NYPD detective turns out to have been an imposter, causing them to question why Paige chose to run from this mystery man, what he wanted -- and if he caught up with her. Further investigation uncovers that the seemingly upstanding and socially conscious Paige was involved in a lucrative identity theft ring with close ties to a terrorist on a watch list who was recently seen in New York with her. Meanwhile, the remaining team members are gravely concerned about Vivian, who is undergoing open-heart surgery on that very day.

Martin and Danny are ambushed by Emil Dornvald, who ends up killing the prisoner they are transoprting. Martin is in serious condition, and a barely wounded Danny is at the end of his rope as he tries to find the man who put Martin in the hospital in critical condition. Jack has his hands full with keeping Danny in check and hunting down Emil Dornvald, the mercenary who had previously worked for General Gamba. Things get sticky when Victor Fitzgerald and Tom Banes of Homeland Security get involved, determined to make a deal with Nuru, whom Jack believes isn't the friendly that Homeland Security believes he is.

After therapist Gina Hill disappears, the team investigates and initially suspects that one of her patients may be involved. After discussions with Gina's fiancé and her own therapist, the team follows the trail of clues to a bartender named Vince with an unusual ability to get good women to do whatever he wants them to. Martin continues to struggle with his recovery.

After attorney Jennifer Nichols disappears, the team investigates the last few days in her life and soon find that she had grown disillusioned with her most recent relationship with Allen Davis. Discussions with a married ex-lover reveal that Nichols had recently gone through an old case file relating to a ten-year-old bank robbery, which has a connection to her recent relationship. Jack and Ann avoid discussing a recent development in their relationship -- her pregnancy.

Bryan Parker is questioned by the FBI after being found alone on the road by a police officer, his hand bandaged. He tells them about a young boy his father had abducted, and soon the team is searching for Todd. The search initially goes nowhere, and Sam continues to question Bryan, but they get a lead when Bryan identifies a snapshot of the boy that reveals his identity to be that of missing boy Daniel Ellison. It isn't long before the squad realises that Daniel isn't the first boy that Parker grabbed, and follow his past to find him and the missing boy.

The team searches for missing water plant supervisor Jason Turner, and learn that he had become the target of a lot of anger after recent layoffs at the plant. Carlos comes to the office looking for Elena.

A child prodigy turned store Santa vanishes and the team wonders if he had criminal connections.

Jack goes missing after taking a case into his own hands which soon becomes intertwined with a human trafficking prostitution case that Vivian is working on.

The team searches for a coma patient who had woken up after three years only to disappear.

A white-collar criminal goes missing on his way to testify against a former associate and the team must find out why.

The team must shift their attention from a case they are working on and hand it over to Martin, after a child is reported to have been kidnapped at a mall.