The Roderick gang’s battle with Legato is violently interrupted by the fierce Gung-Ho Guns. Just as Vash begins to investigate the incident, he meets Dominique the Cyclops, a lethal beauty with an amazing power.

Vash faces off with two of the Gung-Ho Guns: E.G. Mine and Rai-Dei the Blade. When the action heats up, Vash the Stampede is forced to unleash a new and devastating attack.

After Vash faces Midvalley the Hornfreak, he squares off with Legato for a final showdown. Making matters worse, the townsfolk are stuck in the middle of the chaos!