Meryl and Milly seek shelter in the mansion of Cliff Schezar, a wealthy man who has hired Vash as a bodyguard! Have the girls finally found the infamous gunslinger? Or is Cliff hiding something?

During a bus trip to May City, Vash, Meryl, and Milly encounter a priest named Nicholas D. Wolfwood. Before too long, the travelers finds their journey interrupted by a horde of attacking robotic spiders!

An elderly couple asks Millie and Meryl to help them protect a piece of valuable property from their rivals. With hired killers nearby, and Vash nowhere to be found, Meryl and Millie might be in over their heads.

Wolfwood meets Lina, a girl who’s having trouble with a guy who claims to be Vash the Stampede. When she’s abducted, Wolfwood must team up with an odd fellow name Erics to save her.

Vash and the gang meet a group of orphans whose parents vanished after falling victim to a strange trance. Is it Legato’s doing? Or is there a secret villain hidden among the children?

Meryl and Millie are doing their best to get by as Vash recovers, but when the locals discover that the infamous gunslinger is nearby, they set out to make him pay for their recent pains - with his life.