Among the objects left by Roidmude 066 was a map that hints at a second Global Freeze. The Special Investigation Unit receives an investigation request from the newly created SSDC and starts to move. Meanwhile, Gold Drive is searching for Brain to advance his plans for a new Global Freeze. Once Gold Drive, Medic, Heart and Brain are together, the Global Freeze will become a reality. However, another unthinkable character is after Brain.

Brain was cornered by Gold Drive and Roidmude 004, who wished to trigger a second Global Freeze. However, he was saved by Drive. Drive helps Brain escape but Kiriko is wounded in battle. Now aware of his own feelings for her, he feels very troubled while rescuing her. Meanwhile, Brain was looking into Medic’s sudden change after escaping. When he reached the fragment of his claw in Medic’s body and finds out the truth behind the change in her system, he also discovers that his very existence, along with Heart’s and Medic’s, is in terrible danger.