Doctor Reaper returns to Shocker's Japan branch of Katsugawa Island along with Catfishgiller who he remodeled from an electric catfish.

Mutant Chameleon is resurrected as Vampire-Chameleon and Marshal Armor sends him on a mission to collect the blood of innocent children. Kazami Shiro befriends young Kenichi, who is despondent because he believes that he has seen a mutant. When Vampire-Chameleon attacks Kenichi's grammar school, Shiro and Joji find themselves in a dilemma, when they face a horde of vampire children they cannot kill�

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Hiroshi must stop a Neo Shocker monster who has taken the disguise of a nurse trying to kill a little girl she is taking care of.

When an untrustworthy boy sees a Neo Shocker kaijin preparing to destroy a combine, he must convince those who don't believe him to save it.

Hiroshi must stop a killer mold Kaijin from causing a massive earthquake while killing victims with its vegetative onslaught.