Orochimaru is forced to flee the Hidden Leaf after Third Hokage Hiruzen exposes his illegal experiments. Danzo, fearing that Orochimaru’s capture would lead to the exposure of his own involvement in the experiments, sends out one of his men to help.

The Senju and Uchiha clans join together to build a shinobi village and fulfill their dreams.

All the Tailed Beasts are freed, and old friends Kakashi and Obito come face to face with each other. What will Obito's response be? Meanwhile, the Tailed Beasts and the Allied Shinobi Forces shift their focus onto their greatest foe, Madara Uchiha. Gaara is reunited with his former Tailed Beast, Shukaku. When Gaara asks Shukaku to lend his power to seal Madara, he refuses. Will their history of animosity prevent them from working together?