As Brian tries to put his secret feelings for Marjorie aside, Adam and Dave Greco encourage him to live the ultimate single man's dream by hooking up with two different women in 24 hours. Meanwhile, Marjorie experiences mixed feelings when she sees Brian moving on. Deena Greco thinks about the possibilities of an open marriage when she meets a cute divorced dad at her daughter's school, and in their efforts to have a baby, Nic encourages a reluctant Angelo to go to a clinic.

When things go awry the day Marjorie moves into fiancé Adam's place, she doesn't want to interrupt him from his deposition work, so she calls on Brian for help -- forcing the two to take stock of their friendship. Meanwhile, Dave and Brian anxiously await a call from a potential client who could solve their money woes, Nic and Angelo consider their fertility options, and Deena is torn between staying home with her sick child or accepting a date from the cute divorced dad she met at her daughter's school.

It's Saturday and everyone wants something from Brian, but no one can find him. Brian has decided that he would rather spend the day with his new love, Lisa B. Meanwhile, Nicole, hopped up on her fertility hormone treatments, needs her brother to help her and Angelo with a car problem; Deena and Dave expect Brian to play "Barney" at their daughter's birthday party; Adam, stuck planning the wedding, wants him for some guy time; and Marjorie keeps leaving messages on Brian's phone to talk about their relationship.

Brian's apparent interest in his new girlfriend causes Marjorie to unwittingly sabotage the relationship. Dave, who is convinced that Deena is having an affair, turns what was supposed to be a simple golf outing with the guys into a complicated stakeout to catch his wife in the act. Meanwhile, Nicole has told Deena that spouses shouldn't keep secrets from each other, but she's hiding from Angelo that she's taking fertility hormone injections.

Deena's mother, Frankie, comes for a visit and, like everyone else, is unaware that Dave and Deena are back together. Now that Brian has broken up with Bridget, he gets separate invitations from his two attractive downstairs neighbors. Meanwhile, against Natasha's wishes, Brian assigns a big presentation to Dave; Adam and Nicole deal with the aftermath of their unexpected tryst; Dave gets into a fist fight with Deena's ex-lover; and the friends get a surprise when they visit Ivy and Jimmy's home for the first time.

After an embarrassing photo of Brian with fledgling actress Stephanie runs in the tabloids, she's instructed by her manager not to be seen in public with him. So Laura is secretly delighted when Stephanie invites her to go along with them to a hot Hollywood party and act as Brian's date. Meanwhile Deena's new cupcake store struggles until business partner Nicole comes up with a unique way to get more customers; Natasha sets the parameters for her relationship with Adam; and it's time for Deena and Dave to decide if they're going to sign their divorce papers.