Dr. Lu Delgado is running out of money to run her free clinic by herself. When Lu goes to prestigious Rittenhouse Hospital to ask for assistance, famous O.B.G.Y.N./surgeon Dr. Dana Stowe blames Lu for ruining her breast cancer study to find a cure for cancer after Lu tells a woman her opinon about test studies. Dana later is asked by Chief of Staff Dr. Bob Jackson to tour Lu's clinic and see if the clinic should get funded by Rittenhouse . Dana tells one of her patients that she has ovarian cancer and that she will not be able to have any children even though she has the desire to. In the end, Dr. Lydia Emerson comes up with the perfect solution to Lu's problem.

Dana has big problem on her hands when Susan Jackson comes to the hospital with bruises. Dana wonders if Robert Jackson gave her the bruises because their marriage problems. Dana gets the feeling Susan may not be telling her all she knows.

After Dana learns Robert found his wife at the bottom of the stairs Susan tells that had double vision leading Dana to believe Susan might have Multiple Sclerosis.

It's Breast Cancer Awareness Weekend at the Rittenhouse Hospital Women's Clinic, where Lu (Rosa Blasi), Lana (Jenifer Lewis) and Peter (Josh Coxx) are hosting a dance-a-thon and a free mammogram clinic. When one woman's mammogram reveals a lump, she must choose between losing both her breasts and losing her job. After Dana (Janine Turner) delivers the unexpected results of her breast cancer clinical trial, she learns the very disease that's defined her career has now hit too close to home.

Dana takes a leave from the clinic to help her mother through a double mastectomy. Lu's impromptu safe-sex speech at a prep school's career day puts her in the middle of a legal dispute over a date rape. Peter's ""alternative"" approach to pain management for a patient with Hodgkin's disease gets them both arrested. And Dana and Lu must each decide how much they want to know when they are both tested for the mutated BRCA1 and BRCA2 genes that would reveal a predisposition to breast cancer.