A talented young pickpocket named Poco unwittingly lures JoJo and company into an encounter with Dio, Tarukus, and Blueford.

The encounter between JoJo and the Knights continues.

Joseph is confronted by one of Stroheim's men, Donovan, but manages to subdue him, learning that Speedwagon is still alive.

Wanting to teach JoJo to control his Ripple powers, Caesar takes him to Venice to meet his teacher, Lisa Lisa.

Lisa Lisa explains to JoJo and Caesar how the creator of the Stone Mask, Kars, is seeking a perfectly cut Red Stone of Aja known as the Super Aja to power the Stone Mask and become the ultimate life form.

Launching his Final Mode attack, Gathering Gale, which starts peeling away his own body, Wamuu begins firing a stream of wind capable of cutting stone towards JoJo.

Steely Dan's Stand, The Lovers, has entered Joseph's brain. Dan puts himself at an advantage, with having Joseph's life on the line, and tells Jotaro to do various things for him, knowing Jotaro has no choice but to obey. Meanwhile, Kakyoin and Polnareff also enter Joseph's brain with their Stands and find the Stand that is using brain cells as food.

Bucciarati and Abbacchio are the only members of the gang left in the yacht. They have to find out where the enemy stand is hiding and how does it work.

After defeating Zucchero, the gang realizes that he has already told someone else where they were going and why.

Mista chases a Passione member named Sale to stop him from finding Polpo's treasure.

"Take Trish to Venice." With their next order from the boss, Bucciarati and his crew head to Naples Station. "Use the key at the water fountain with the turtle on the 6th platform." They find the water fountain, but can't find the place to use the key. Meanwhile, Proscuitto and Pesci from the Hitman Team follow Bucciarati and the others to Naples Station. Bucciarati figures out the mystery behind the key and gets on the express train to Florence, and Proscuitto and Pesci follow.

The Grateful Dead slowly begins to age everybody on the train. With his teammates affected, Mista goes alone to confront the enemy, only to encounter Pesci and his Beach Boy.

After defeating Squallo and Tiziano, Bucciarati and the others head off to Sardinia to find out about the boss's past. They head to Marco Polo International Airport in order to get a jet, but a strange man was following them. Mista manages to kill the strange Stand user before they're able to call upon their Stand. Even though they're a bit put off at how simple that was, they get onto the jet and fly off. But once they're on the jet, Giorno hears a weird noise...

Trapped in the cabin of a flying plane with Notorious B.I.G, Trish has noticed that Giorno's brooch is turning into a brand new hand that will allow him to regain his powers. However, the movement of the transformation is attracting the enemy Stand. As the plane approaches the Tyrrhenian Sea, Trish must now try to protect both the hand of Giorno and herself from Notorious B.I.G.

While Bruno stays on the ground to fight against Secco's Oasis, Giorno and Mista head upwards towards Cioccolata to stop the power of his Green Day. But Cioccolata has another dangerous trick up his sleeve, pushing the two into a corner.

Bruno and Secco are both racing towards the man at the Colloseum whilst trying to kill each other.

The Stand arrow's rightful owner is finally revealed.

Pale Snake's user, Father Pucchi, makes his entrance. A baseball game in the yard against Miraschon heats up when F.F. and Stone Ocean get involved.

Father Pucchi learns some damning information. Jolyne and Weather's bodies strain under Jumpin' Jack Spark's Stand ability as the fight continues.

In a bid to find the bone, Jolyne intentionally gets sent to the Ultra Security House Unit. Hoping to save her, F.F. turns to Anastasia for help.

The Stand Survivor sparks brawls throughout the Disciplinary Wing. While fighting off a prison guard, Jolyne realizes that he is also a Stand User.

In a boat piloted by the obedient YA-YA MA, Jolyne and Anastasia flee through the wetlands. However, YA-YA MA attacks them with an invisible ability.

After realizing the connection between Father Pucchi and Pale Snake, F.F. defeats D an' G. As YA-YA MA disintegrates, the egg it swallowed hatches.

Weather Forecast summons some rain, which saves F.F. from the brink of destruction. They reunite with Jolyne and Anastasia, but the group gets attacked.

Jolyne learns a shocking truth about Weather Forecast after her fight with Rikiel. She and Ermes enter the hospital and find a hole dug in the floor.

Trapped by Versus's Stand in the memory of the crashed plane, Jolyne leaps from the aircraft and launches an attack, but it fails to affect Versus.

With Weather Forecast's Stand disc in hand, Jolyne and her allies head to Cape Canaveral in pursuit of Father Pucchi, whose body begins to change.