England, 1868. A thief tries to raid an overturned carriage, but discovers that two of the occupants, a man and his young son are still alive. The man, George Joestar, proclaims he will forever be indebted to his savior, who reveals himself to be Dario Brando.

Seven years later in 1888, JoJo and Dio are supposedly getting along, though JoJo is still fearful of Dio. Meanwhile, Dio plots to liberate the Joestar family of their fortune.

JoJo prepares to turn Dio in to the police.

Three days after the incident, JoJo awakens to find Erina nursing him back to health in the hospital. As they rekindle their friendship, they encounter a strange man named Will A. Zeppeli.

A talented young pickpocket named Poco unwittingly lures JoJo and company into an encounter with Dio, Tarukus, and Blueford.

The encounter between JoJo and the Knights continues.

The encounter against Tarukus comes to an end. Poco's family is in grave danger. JoJo meets Dire, Straizo, and Tonpetty.

The party are received by Doobie. Dire faces off against Dio. Straizo takes on Pajyu, Jones, Pluton, and Barnum.

As Dio falls following his battle with JoJo, he decapitates himself before the ripple reaches his head, which is recovered by his zombie servant Wang Chung.

In 1938, 49 years after Jonathan Joestar's death, Speedwagon and Straizo travel to Mexico, where they discover an underground room filled with similar looking masks and a petrified body believed to be the being who created them.

As expected, Straizo recovers from Joseph's attack and uses the laser eye attack Dio used to seemingly pierce through JoJo's head and neck. However, this turns out to be a clever trick by Joseph.

Joseph is confronted by one of Stroheim's men, Donovan, but manages to subdue him, learning that Speedwagon is still alive.

As Joseph begins to fight against Santana, Joseph finds his Ripple to not be effective against Santana, but it still helps protect him from the Pillar Man's attacks. Joseph appears to be unconscious after receiving a powerful hit.

Speedwagon brings statued remains of Santana to the headquarters of his foundation in Washington, D.C., where it is shown Santana is still alive, but his scientists are able to keep him dormant through the use of ultraviolet light.

Caesar engages Wamuu in battle for killing Mark, using his Bubble Launcher technique to surround the Pillar Man in Ripple enfused bubbles.

Wanting to teach JoJo to control his Ripple powers, Caesar takes him to Venice to meet his teacher, Lisa Lisa.

Lisa Lisa explains to JoJo and Caesar how the creator of the Stone Mask, Kars, is seeking a perfectly cut Red Stone of Aja known as the Super Aja to power the Stone Mask and become the ultimate life form.

As JoJo awaits to warn Lisa Lisa about the Pillar Men, Esidisi's brain takes over the body of Suzi Q and sends the Super Aja off on a boat bound for Venice before confronting Lisa Lisa.

Stroheim starts using his new mechanical body, which was designed to surpass Santana, to fight against Kars. However, it proves futile against Kars' Light Mode.

Lisa Lisa tells JoJo of Caesar's childhood, in which he took to crime at a young age after being abandoned by his debt-ridden father, Mario.

Whilst following Wamuu's trail of blood, JoJo and Lisa Lisa encounter another vampire named Wired Beck.

Before JoJo's and Wamuu's race begins, it is revealed that during each lap, there will be a different weapon for whoever can grab it from a pillar first.

Launching his Final Mode attack, Gathering Gale, which starts peeling away his own body, Wamuu begins firing a stream of wind capable of cutting stone towards JoJo.

Being forced to cling onto a rope to stop Lisa Lisa from falling to her death, JoJo is at a huge disadvantage against Kars.

Kars demonstrates his new powers, turning his hand into a flesh-eating squirrel that deals damage to Stroheim. The sun rises, leaving a shocking discovery.

JoJo's victory, along with his arm, is cut short when Kars manages to survive the volcano by forming a shield of air bubbles to protect him from its deadly lava.

Koichi arrives in Italy on a mission from Jotaro to find Giorno; they meet haphazardly when Giorno steals Koichi's luggage, and the ensuing chase leads Giorno into a Stand battle with the gangster Leaky Eye Luca.

Faced with Bucciarati's Stand, Sticky Fingers, Giorno desperately uses Gold Experience to defend himself.

Giorno is interviewed by a strange man to enter the Passione gang and achieve his dream of becoming a "Gang-Star".

After apparently failing Polpo's test, Giorno is attacked by his stand, Black Sabbath, who tries to pierce his soul with a stand arrow.

News of Polpo's death reach the organization, along with word that he had a huge fortune hidden somewhere. Meanwhile, Giorno meets Bucciarati's gang.

Bucciarati and Abbacchio are the only members of the gang left in the yacht. They have to find out where the enemy stand is hiding and how does it work.

After defeating Zucchero, the gang realizes that he has already told someone else where they were going and why.

Mista chases a Passione member named Sale to stop him from finding Polpo's treasure.

After being promoted to capo, Bucciarati and his gang are tasked to protect the boss' daughter.

Narancia discovers that he is slowly shrinking due to the wound Formaggio's stand, Little Feet, had inflicted on him.

Formaggio traps the now miniature Narancia beneath his foot and attempts to interrogate him, but Narancia resists. A flashback shows Narancia's early life on the streets and his rescue by Bucciarati.

In order to protect Trish from the Hitman Team, Bucciarati and crew's second mission from the boss was to go find a key in Pompei for some kind of vehicle that should aid them later on. Following orders, Giorno, Abbacchio, and Fugo head to Pompei to retrieve the key. When they get there, Fugo notices a suspicious shadow reflecting in a mirror that happened to be placed on one of the pillars there...

The person hiding in the mirror was Illuso from the Hitman Team. Fugo ends up being dragged into the mirror by Illuso's Stand, Man in the Mirror. Fugo then summons his own Stand, Purple Haze. Despite Giorno wanting to find Fugo, Abbacchio decides to go look for the key, since that was their mission. However, once Abbacchio finds the key, he also gets dragged into the mirror world...

"Take Trish to Venice." With their next order from the boss, Bucciarati and his crew head to Naples Station. "Use the key at the water fountain with the turtle on the 6th platform." They find the water fountain, but can't find the place to use the key. Meanwhile, Proscuitto and Pesci from the Hitman Team follow Bucciarati and the others to Naples Station. Bucciarati figures out the mystery behind the key and gets on the express train to Florence, and Proscuitto and Pesci follow.

The Grateful Dead slowly begins to age everybody on the train. With his teammates affected, Mista goes alone to confront the enemy, only to encounter Pesci and his Beach Boy.

Number Six from Sex Pistols manages to warn Bucciarati about the enemies and fights back, but The Grateful Dead's powers are taking a toll on him. Bucciarati steels his resolve and throws himself out with Prosciutto out of the train that's going 150kph. Barely hanging onto life, Prosciutto uses The Grateful Dead again. Pesci decides to take Prosciutto's resolve to heart and attacks Bucciarati.

After defeating Proscuitto and Pesci, Bucciarati and the others head to Venice in a car. Melone from the Hitman Team finds some of Bucciarati's blood at the scene where the train had stopped and then activates Babyface. The powerful remote-control Stand created by assaulting a woman on the train then goes after Bucciarati.

Using Babyface's Stand's ability to turn human parts into other things, Giorno uses his Golden Wind to make parts for the human body. He rebuilds his own body and fights back. Meanwhile, another member of the Hitman Team who's also after Trish, Ghiaccio, was trying to regroup with Melone and was driving to Giorno's location.

Ghiaccio's Stand, White Album is able to envelop him like a bodysuit and able to freeze everything around him to extremely low temperatures. Giorno and Mista somewhat make it to Venice, despite being partially frozen by Ghiaccio. But in order to try to get away from Ghiaccio, Giorno drives their car into the canal and they get stuck. Mista tries to sacrifice himself, but Giorno tells him that what's important right now isn't for him to sacrifice himself but for him to have resolve.

Mista and Giorno were able to defeat Ghiaccio. They then confirm the mission on the disc and head to the location they're supposed to take Trish. Bucciarati goes up the tower with Trish, but while they're in the elevator, Trish suddenly disappears. Bucciarati then realizes what the boss's true motives are.

Bucciarati finds out that the boss's true motive is to eliminate Trish because of her relationship with him, causing him to betray the boss and save Trish. Meanwhile, Giorno feels something bizarre is going on as they waited for Bucciarati's return. The boss's Stand, King Crimson rises.

Because of their own wills and their sense of justice, Bucciarati and the others end up betraying the organization. Trish also wants to find out who her father truly is, so she tells the others that her mother met her father in Sardinia. They all decide to have a meal in Venice before they leave and Narancia is suddenly attacked by a Stand. The boss's own personal elite guard was now on the move.

The Stand that attacked Narancia was named Crush and belonged to Squallo, a member of the boss's elite guard. On top of that, Narancia suddenly can only say the exact opposite of what he's thinking, thanks to the ability of Talking Mouth, the Stand of Squallo's partner, Tiziano. Using Narancia, Squallo and Tiziano throw the team into chaos. The two elite guard members put Narancia in danger, but he boldly faces them so they can get out of Venice safely.

After defeating Squallo and Tiziano, Bucciarati and the others head off to Sardinia to find out about the boss's past. They head to Marco Polo International Airport in order to get a jet, but a strange man was following them. Mista manages to kill the strange Stand user before they're able to call upon their Stand. Even though they're a bit put off at how simple that was, they get onto the jet and fly off. But once they're on the jet, Giorno hears a weird noise...

Trapped in the cabin of a flying plane with Notorious B.I.G, Trish has noticed that Giorno's brooch is turning into a brand new hand that will allow him to regain his powers. However, the movement of the transformation is attracting the enemy Stand. As the plane approaches the Tyrrhenian Sea, Trish must now try to protect both the hand of Giorno and herself from Notorious B.I.G.

On the island of Sardinia, a boy named Doppio is searching for Trish and the others on orders from Passione's boss. But Doppio has a dark secret, one that becomes apparent when he encounters Risotto of La Squadra.

Doppio, the alter ego of Passione's boss, continues to fight against Risotto and his iron controlling Metallica. Doppio struggles against the powerful assassin, but is armed with King Crimson's Epitaph, which allows him to see the future.

In the aftermath of the battle between Risotto and Doppio, Abbacchio uses Moody Blues to try and uncover the boss's identity. But the boss is adamant about keeping his identity a secret and executes his next gambit against the group.

After his death, Abbacchio was able to leave the others a copy of the boss’s face and fingerprints with Moody Blues' replay. The others try to find out who the boss is with the fingerprint and suddenly get contacted by someone. The mysterious man tells them that the boss’s name is Diavolo and tells them that the secret behind defeating him lies in the arrow. Bucciarati and the others head to Rome to meet him.

The gang are under attack by the last two members of the Elite Squad. Cioccolata uses his Green Day to spread a toxic mold over the island while Secco uses Oasis to swim through rock for stealth attacks, leaving the gang in a pinch.

While Bruno stays on the ground to fight against Secco's Oasis, Giorno and Mista head upwards towards Cioccolata to stop the power of his Green Day. But Cioccolata has another dangerous trick up his sleeve, pushing the two into a corner.

Bruno and Secco are both racing towards the man at the Colloseum whilst trying to kill each other.

Bruno unknowingly leads Doppio to the Colosseum while the rest of the gang is searching for their leader.

Everyone wakes up from a deep sleep to discover their souls have been swapped.

The gang desperately tries to reach the Stand arrow whilst looking for Diavolo.

Everyone continues to desperately chase after the Requiem in order to obtain the Stand arrow. Diavolo's soul is then forced to show itself, but he will not quit until he obtains the arrow for himself.

The Stand arrow's rightful owner is finally revealed.

Giorno achieves his dream and destiny of becoming a Gang-star.

In the past, Bruno and his team investigated the mysterious death of a girl and how it ties into the power known as Rolling Stones. And in the present, the final fate of Giorno and the gang is revealed as Golden Wind comes to a close.