Ben Hollander is a distraught architect whose degenerating eyesight causes him despondent while a spirited new nurse, Samantha Taggart joins the staff. Elsewhere, disaster strikes when the doctors suspect a mother is abusing her child while Dr. Corday learns something shocking about the charismatic Dr. Dorset, and Dr. Archie Morris is overwhelmed by the chaos and grisly conditions of life in the E.R.

Pratt and Kovac clash over a miscarriage-prone young woman, Denny, who arrives to deliver a premature baby. Pratt wants to make heroic efforts to save the unborn child, while Kovac is adamantly against spending vast amounts of money to keep the forever sickly baby alive.

To everyone's amazement, Lewis makes a date to share a home-cooked dinner with the elderly Ben Hollander, her depressed patient who is going blind.

On Thanksgiving Day, a helicopter crash outside the ER leaves several injured, and kills Dr. Romano. Alex tries to bring Sam and Luka together.

Neela helps treat two Amish teens who were in a car crash. Sam argues with Dr. Kovac when he pays too much attention to her son.

Carter returns to County General to hearty welcomes. Although Abby is shocked to learn that Carter's beautiful African girlfriend, Kem, is already pregnant with Carter's child, Abby has moved on with her life as well, going back to medical school.

Abby and Neela are assigned to a month-long rotation in the neonatal intensive care unit where they experience emotional roller coasters while caring for the sick infants.

Dr. Carter's girlfriend makes an impression as she observes ER operations. Dr. Gallant is almost shot during a domestic incident. Dr. Weaver dedicates a center to the memory of Dr. Romano.

Sam treats an abused, pregnant teen. Dr. Carter introduces African girlfriend Makemba to wintertime. ER chaos shocks a risk-assessment expert. Dr. Pratt and Abby restrain a man who has tuberculosis.

Carter misses his pregnant girlfriend who has returned to Africa. A family of four is rushed to the emergency room after suffering carbon monoxide poisoning from their faulty furnace--forcing the claustrophobic Neela to accompany a newborn baby into an extremely uncomfortable hyperbaric chamber.

Morris streets a patient without getting a psych consult, and the guy steals a tank and heads for County. Gillian is visiting Luka, and Sam's not happy about it. Luka and Sam make up by the end of the day though. A 13-year-old boy has chlamydia. Frank has a heart attack. Corday plays the dating game, going out with two men.

Carter sticks up for Neela when the other attendings doubt her future in the ER. Neela caves to the pressure and accidentally gives a patient the wrong medication. Gallant takes the blame for her though. Sam and Luka try to plan Alex's birthday party. Frank visits on his way to therapy. Chen's home nurse quits after her dad behaves poorly.

Weaver rushes to the aid of her female life partner, Sandy Lopez, when the firefighter is severely injured while working and must now battle for her life. Frightened Weaver whispers hope to Sandy by reminding the victim of their newborn child.

Pratt struggles to diagnose a woman who suffers mysterious chronic seizures. An attractive woman, Campbell, informally accuses flirtatious Pratt of sexual harassment. Abby ponders how to get her contentious patients' attention during her psychiatric department rotation.

A panic-stricken Weaver is ordered to give her son to the Lopez family. Carter greets the returning Kem, but their meeting with his father, Jack, gets tense after Carter announces plans for his grandmother's estate.

Carter takes Kem to the hospital to check on their baby since it's not kicking anymore.

Kovacs stops to help a woman and her son whose car broke down. Steve is getting close to Alex, and Sam panics. Abby is looking for her letter whether to see she passed her boards. Pratt shows off his new Chrysler. Elgin tries to build a connection between him and Pratt. Jing-Mei might be battered by her senile father.

After being shot at, Pratt, Jing-Mei and Elgin are trying to get of their sinking car. Sam took Alex with her while fleeing for Steve, Kovac is considering to go after them. Abby wants to go to bed since tomorrow is her first day as a doctor, but is thwarted by Weaver, whose custody battle might take a dramatic turn. A young drug-dealer is brought in with "a foreign object" in her tunnel of life.

Neela is still struggling with her decision not to continue becoming a doctor. We discover that Ray is in a band. Kovac and Sam are amoureux, but where does that leave them?

It's a busy Fourth of July and Carter is the only attending working.

Carter, Pratt, Kovac and Abby are dealing with a woman and her three children who've jumped from a three floor apartment trying to escape from the father. Meanwhile Dr. Lewis becomes Chief of Emergency Medicine, Howard quits his internship and Dr. Corday is facing dismissal.

Neela starts a new job in the emergency room after working at the convenience store near the hospital. On Neela's first day, Pratt expects the interns, Abby, Ray and Neela, to take on a large patient load during their shifts. Pratt turns processing the patients into a competition, in which Ray is clearly going to be the winner.

The last 44 minutes of ex-con & alcoholic Charlie Metcalf's life are in the ER, as he slowly succumbs to end-stage liver failure.

A rape victim, barely able to speak, does all she can to help police find her attacker.

A wounded police officer's teenage son must make a life or death decision. Abby tries to convince a girl needing appendicitis surgery to stay at County, but her fathers wants her transferred to another hospital.

Abby has a dialysis patient in critical condition, but she cannot find his physician, who does not want to be bothered during the holidays.

Gang members kidnap Abby hoping she can save one of their members with a gunshot wound. Ray starts treating a patient, but when she requests a new doctor, he gets offended.

Two teens enter the ER with gunshot wounds. When one dies, Neela botches telling the next of kin, making the woman hysterical.

When a 16-year-old girl who had received a kidney transplant from her father arrives at the emergency room feeling dizzy, Carter traces the problem to a new drug that the girl was taking to control seizures related to her kidney dysfunction.

While examining a young boy, Pratt finds a suspicious gash across his chest and calls Wendall (recurring guest star MäDCHEN AMICK) for a consult. Kovac and Pratt examine a man who was shot when he confronted his boss with a gun. Jake (recurring guest star EION BAILEY) tries to convince Abby to date him despite his being a student.

Dr. Weaver meets her birth mother, but their relationship changes when Kerrie reveals she is gay. Dr. Carter causes a commotion when he confronts a couple hoping to scam some painkillers.

A soccer mom finds herself completely aware of everything going on around her, but is unable to move or speak after suffering a stroke.

Neela (who's in Chicago) and Gallant (who's in Iraq) miss each other and write letters. Gallant also tries to save the life of a little girl.

Sam's ex-husband shows up and wants to take Alex on a trip. Gallant is back and Neela hopes to see him before he goes back to Iraq.

A woman on a hunger strike refuses treatment until the INS give her son another deportation hearing. Abby searches for proof when she suspects a patient is the victim of elder abuse.

Jules 'Ruby' Rubadoux is back in the ER. He's still angry with Carter about the death of his wife.

Morris is named the new chief resident, which makes nobody really happy, except Morris. Meanwhile Luka and Sam are having communication problems, Carter gets a promotion Susan really wanted and Ray finds out a 14-year old who always comes in for free drugs has been raped.

After Carter finds out Kem's mother is hospitalized in Paris he decides to go there to tell Kem how he feels about her. Meanwhile, Ray makes a fatal error.

Casualties of a disaster flood the ER, which is short-handed because everyone is at Dr. Carter's going-away party because he's leaving the ER after 11 years. Dr. Pratt looks for the courage to confront his father, Charlie.

Sam and Luka go on the search for her runaway son, Alex. Meanwhile, Pratt and Lewis guide Abby, Neela and Ray, who have become R2's, on how to teach the new interns.

Much to Ray's dislike, a surrogate mother in labor doesn't want to have a C-section and endangers the life of the baby. Meanwhile, Sam tells Luka she and Alex are moving out. Pratt meets his half-brother and -sister, and Abby makes a difficult decision about a young boy.

Luka has a very bad day: New nurse manager Eve Peyton notices he doesn't want to work with Sam and tells him so. At the end of the day he's drunk and Abby takes him home.

The rainy night brings in diverse patients including a mother involved in a car accident with her baby, a man with a satisfaction facilitator, and a comatose patient who suddenly wakes up. Also, Sam steps up to Eve and her strict ways and Jerry gets struck by lightening!

A new attending, Dr. Victor Clemente, comes aboard and quickly makes a stir on the ER. Abby's breast cancer patient convinces her to take a long awaited test. Luka befriends a young woman who awakes from a six-year coma. Also, Weaver shows Clemente who runs the ER.

Pratt's half-brother tries to get him to make ends meet with his estranged father. Clemente treats an infant chimpanzee and involves Abby and Neela on the secret case. Eve promotes Sam and her first tasks is to fire a beloved nurse.

A kidnaped girl is the victim of police shooting. Abby is stuck in the middle of a disagreement between Luka and Clemente. Neela receives a phone call from Iraq. Later, Luka and Abby share a kiss.

The ER prepares to take in victims from a plane collision, while Neela and Pratt head out to the crash site where Neela makes heroic efforts. At the end of the day, Neela gets a surprising visit.

Gallant impulsively asks Neela to marry her that exact day, she says I do but soon gets cold feet. Morris stands up to Weaver on a patients course of treatment. Luka, Sam and Clemente treat a boy who contracted HIV from his mother. Also, Abby and Luka redefine their relationship and Luka is named the new Chief of Emergency Medicine.

Pratt and Weaver try to create a Christmas miracle when they work to save a girl wounded from gunfire. Eve gets into trouble after punching a disruptive patient. Also, Abby has a special gift for Luka.

Neela treats a religious teenage girl who turns out to be pregnant. Abby and Kovac struggle to figure out what to do with her unexpected pregnancy.

Ray helps an old friend escape from her abusive father. Dubenko volunteers in the ER but can't seem to handle a slow day. Abby and Kovac go baby shopping, while Neela gets unexpected and upsetting news from Gallant.

Dr. Nate Lennox, a former professor with ALS, is brought in as the progression of his disease is chronicled through his own flashbacks as he is treated by each of the doctors at one point. As Lennox wants to give up, Abby fights to convince him to keep on fighting.

An unexpected visitor puts Clemente in the middle of a domestic dispute. Meanwhile, Luka and Abby await test results on their unborn child; Neela struggles with her surgical elective and Pratt ends up with an unexpected suitor when he participates in a charity bachelor auction.

In the Sudan, Carter and a colleague struggle to save a woman who was raped by a band of militants. Back in the ER, Clemente asks to return to work after the shooting incident, but Kovac refuses. Meanwhile, Neela and Pratt have a work dispute, and, in a related incident, K.J.'s father shows up again in the ER.

When is it time to go out on a limb? Armand Assante guest stars as a patient who makes Sam an offer she might not be able to refuse. Luka must calm Abby’s baby-related fears after an incident at the hospital places everyone at risk. Kerry makes a difficult choice, and Neela joins a support group.

Abby and Luka desperately try to keep a young woman brought into the ER with stab wounds to the neck alive. As her condition begins to worsen, Clemente steps in and tries a risky procedure on the girl in order to save her life. Meanwhile, Neela pulls an all-nighter in preparation for a speech at a surgeon's convention, Ray treats a man claiming to have swallowed a bottle of pills, and Sam decides to take a part-time job with Richard to help her with childcare expenses.

When Luka answers a call for help, he discovers not everyone is pleased. Will he honor his commitment, or ask a colleague to step in for him? Abby and Morris wrestle with the strange case of a car crash victim. Having made a change in her life, Sam finds herself enjoying a few new perks. Neela has unexpected visitors, with even more unexpected news.

Pratt departs for Africa with attitude to spare but makes his first contact with harsh reality before the plane lands. Abby senses something is not what is seems when she treats a 12-year-old and her grandmother, then differs with Luka over the best course of action. A prisoner is brought to the ER with what everyone thinks is a fake case of appendicitis. Morris is dressed, and ready, to impress, but Albright’s not. It’s time for Kerry to return to work and Clemente doesn’t know when it’s time to leave.

Pratt gets to work in Darfur alongside Carter and his co-workers, but is troubled by astounding number of people needing care and finds himself making a dangerous journey.

Pratt struggles to get a straight story when two abused boys come into the ER with their father. Two U.S. Army officers enter the ER.

Chaos reigns in the ER when two prisoners are brought in for treatment, but instead plot a violent escape. Their desperate actions place one doctor in harm's way, and forces one nurse to become a tool in their plan.

Weaver, Kovac, and the other doctors work frantically to try to save Jerry and a pregnant Abby, who were both critically injured during the shootout that left the ER in shambles. Meanwhile, Sam tries to escape from her ex-boyfriend and his criminal accomplices as they head north, but things quickly turn violent.

As Abby and Luka cope with their newborn's life and death struggle, the couple is shocked to receive a surprise visitor: Abby's mother Maggie. Meanwhile, Sam fears the prospect of criminal charges; Neela discovers that Tony Gates will be joining the ER team as an intern and Morris gets his job back while Weaver gets demoted.

Gates is assigned to the case of a closeted gay man whose partner clashes with his family; Neela meets her new surgical chief, Dr. Crenshaw; and Pratt must cope with the flood of new interns.

Abby and Kovac discover both the joys and difficulties of raising a newborn; Morris is wrongfully accused of being a child molester; Pratt has his trial-by-fire when he has to handle the ER alone, juggling multiple traumas, teaching duties and a troublesome intern. Neela continues to be the target of her difficult supervisor, and Sam discovers her sons latest extra-curricular activity.

Curtis Ames, a carpenter who suffered a stroke under Kovac's care, sues him for malpractice. Kovac and Ames square off in court as each man's recollections of Ames' treatment are recounted via testimony and flashbacks. Meanwhile, Abby returns to work and must adjust to the dramatic changes in her life, and Pratt's early morning trip to the barbershop results in a new awareness of community need. Also, Abby and Pratt try an unconventional method for treating a heart patient and Neela tries a risky procedure which doesn't sit well with her chief.

Kovac anxiously awaits the verdict between himself and Curtis Ames but fears the worst. Meanwhile, Neela disobeys her chief's orders and also questions her feelings for Gates, and Weaver unwittingly steals the spotlight from Morris in his big television debut.

A belligerent young man with the flu turns out to be more than he seems, and presents a challenge to Morris and Sam when he refuses treatment. Abby's chance encounter with Curtis Ames leaves Kovac uneasy. Meanwhile, Pratt discovers a local church's risky drug exchange program, Neela and Gates square off, and Weaver gets an interesting offer.

A mysterious illness leaves little hope when a group of homeless kids enter the ER and one of them believes that Neela is a guardian angel in blue; Abby and Kovac clash over a possible case of domestic abuse; Pratt makes a shocking discovery about his brother, and Weaver is unexpectedly called into action when her television appearance becomes a real emergency.

Thanksgiving at County is quiet, with the normal number of routine (or nearly so) emergencies. But Abby makes up for the lack of excitement while returning to the hospital as the doctor on a helicopter transport.

Kovac and Gates treat a girl who appears to have been assaulted. When the police are no help with Ames, Kovac decides to confront the problem himself; Morris and other doctors work on a patient with an ice pick in his ear. Meanwhile, Ray tries to keep his new relationship a secret and Pratt can't fully deal when his half-brother officially comes out. Also, a new male nurse arrives.

It's Christmas in the ER. A homeless boy sends Gates and Ray on a mission. Meanwhile, in the ER, Neela oversees an unusual kidney transplant case; Sam takes a stand when a patient is dumped in an alley by another hospital; and Morris plays Santa for a special girl and learns the meaning of Christmas.

Weaver cares for a Katrina survivor who's reluctant to having surgery on her foot; budget cuts force Luka to make a difficult personnel decision. Also, Gates' home life intrudes on the ER; and Pratt and Hope are shaken after a patient in their care dies needlessly.

Kovac reacts negatively when he sees Abby giving extra attention to a patient; Ray and Gates clash over a patient, pinning Neela in the middle; and Ben takes things to the next level with Sam. Meanwhile, Pratt is under investigation and Weaver says a final goodbye to the ER.

Kovac finds himself in a tense confrontation with Curtis Ames, and Abby must act to protect her family. Meanwhile, Neela and Gates rush to get Meg to the hospital while Sam's new home is soon under threat from fire.

Abby and Sam try to treat an obnoxious, aspiring comedian with mysterious symptoms; Pratt must defend his actions in front of the medical board; Neela scrubs in on a kidney donor transplant; and Morris, as the lone attending, must run a busy ER. Also, Kovac gets a surprising proposal from Abby.

Kovac and Gates find themselves with a moral dilemma when a woman comes into the ER with acute liver failure; Neela finds herself questioning what is right when Manish decides to give up a kidney to a complete stranger. Meanwhile, Ray fights to get to the bottom of a cheerleaders accidental fall; Abby gets a prediction for her future; and Alex's troubles continue to intrude on Sam's work life.

A blizzard strands a family in the snow and Abby and Pratt quickly try to save the family. A gang shooting challenges Morris and Pratt. Meanwhile, Kovac and Abby begin making wedding plans, but their engagement might not be very secret; Gates struggles with the reappearance of his father and the possibility of losing Sarah; and Neela becomes jealous when Dubenko brings in a new surgical intern.

It's Sam's birthday, but she finds it hard to be away from her son Alex. Meanwhile, Sam meets a photographer taking pictures of a terminal patient and she gives Sam a new perspective on life. Dubenko's new surgical intern unsettles Neela during a trauma; Gates is shadowed by a new and nerdy intern and later must tell Sarah the truth that he may be her biological father. Also, Morris and Hope annoy Kovac and Abby when they try to help with their wedding preparations.

Kovac and Gates deal with a hopeless father whose son succumbs to heart failure; Pratt tries to resolve the tension between him and his brother; an Armenian man tries to be a good samaritan but ends up crashing near the ER; Abby sneaks in baby Joe when she worries his sickness may be worse than it seems; Also, Sam injures the instructor of a self-defense seminar.

In 12 hours, the ER will shut down. As Kovac is under pressure to take care of the patients before the final hours, he makes a pivotal decision about his future. Meanwhile, Sam befriends a photojournalist who returns only this time she's terminally ill; Pratt is concerned when his brother ends up in the ER drunk; Morris confronts Gates when he ignores his orders and angrily sends him home while Gates tries to defend his actions.

What is suppose to be a departmental dinner organized by Kovac turns out to be the surprise of a lifetime for Abby when she soon learns it's a surprise wedding, secretly planned by the eager groom. Meanwhile, at the wedding, ER staffers enjoy themselves with music and booze while Neela finds herself the center of unexpected attention between Gates and Ray, which leads to a drunken fight and a shocking conclusion.

Dr. Kevin Moretti, an ICU specialist bent on change, joins the ER team. Change comes elsewhere as Luka and Abby adjust to being husband and wife, Pratt tries to be a new man to his lady friend, Morris and Hope take things to the next level, and Ray goes missing. Later on, Luka gets a troubling phone call.

Season Finale: Luka postpones his honeymoon, leaving Abby, Joe and the ER behind to begin a different journey. Meanwhile, it's Moretti's first day as Chief of Emergency Medicine, and everyone feels the effects of his style, especially Pratt and Morris. Neela learns of Ray's fate, then joins an anti-war rally and finds herself in a dangerous situation. Gates faces a crisis on the home front.

Season Premiere. Moretti's first day is challenging as the ER is inundated with casualties from the peace rally - including Neela. Dubenko faces a crisis in surgery. Abby, Pratt and Morris conspire about how to deal with a shared problem. A new intern arrives unexpectedly, and Gates is reassigned.

Moretti begins to make his presence felt, as he implements changes in the way patients are seen. The ER staff differ on how procedure when a patient comes in with a bullet in him needed as evidence. Neela finds herself the object of more attention that she wants, or needs. Abby had passport woes, and struggles with the changes being made. Pratt and Morris find themselves forced to defend their actions, Hope prepares for a new mission, and Gates finds himself labeled the reject in his new assignment.

Two wounded police auxiliary officers present challenges in the ER. Neela settles in with Abby as she recovers, while Pratt and Bettina consider their relationship. Gates tries to get a patient on a drug trial, with Dubenko's help. And Morris is in a funk that not even a pretty woman can help.

When Baby Joe is injured by a fall at the playground and rushed to the hospital, Abby is unable to reach Luka to tell him.

Moretti reassigns Gates back to the ER and treats a couple involved in a car accident. Morris prepares to take his written board exams. Neela is assigned a young genius intern. Kovac plans to extend his stay in Croatia while Abby struggles with single parenthood.

Morris and Pratt cram for their medical boards when Morretti brings in a new attending physician to help with the load. Sam and Abby work on an attention-hungry patient who comes into the ER with elusive symptoms.

A power outage strikes on an unusually hot day, bringing nursing home patients suffering from hyperthermia to the ER. Abby and Pratt disagree about diagnostic tests for a fussy baby. Morris and Pratt get their board results, and the ER staff celebrates at Ike's. Moretti and Abby's interactions intensify, and Abby finds herself at a dark and frightening crossroads.

Everyone at the ER is happily surprised to see Luka back from Croatia. Great news awaits Neela. Sarah once again needs rescuing by Tony, and patients are causing problems for Morris.

It's time for changes at the ER when Anspaugh makes an unpopular decision. Abby has old demons to fight with, which distance her from friends and family. Even Luka seems to be at a loss to help Abby. Love is in the air when a secret romance blooms between two doctors.

ER's 300th episode finds Luka and Abby hurriedly preparing to travel to Croatia after Luka's father passes away. Luka confronts Abby about the estrangement between them, and she eventually reaches out and asks for his help. A man rushes to the ER when his wife is seriously injured in a car accident, and finds someone very unexpected there with her. Julia holds a service to bless the ER and remember the patients that have been lost through the years.

After being passed over for Chief of the ER, Pratt is looking for a hospital that will appreciate his talents. A former employee of the ER brings her sick son in for tests. Neela's cousin is in town for a visit, and Morris and Harold compete for her affections.

Abby is back from rehab and finds herself the object of scrutiny. She confesses to Pratt that Luka might stay in Croatia longer than planned. Harold seems to have won over Neela's cousin. Multiple victims from a fire fill the ER.

Neela's short visit in Ortho turns into a game of hockey. Bettina wants to take her relationship with Pratt to the next level, but Pratt is not keen on the idea. Gates and Sam disagree over a patient. Julia provides some spiritual guidance in order to ease a prison doctor's bad conscience.

Pratt and a new doctor on the scene disagree on how to teach the interns. Gates treats a young woman with serious heart problems. Abby heads to Croatia, and ponders whether and how to tell Luka about her unfortunate choices. Sam discovers that Julia has moved on in more ways than one.

Neela, worn out after being on shift for over 24 hours, has to make a quick decision regarding an accident victim's torn aorta. Sarah's grandparents are in town, and Hank is rushed to the ER after collapsing during an outing. Gates tries to convey to Sam that his feelings for her are serious.

Kovac is in Chicago looking for hospice-care work. Neela's aorta surgery has caused an infection in her patient. Abby treats a teen who has been beaten up. Brenner continues to cause problems for the ER staff.

There's been a jewelry robbery in town, and Neela finds out that one of her patients might have had something to do with it. Pratt makes an effort to save his relationship with Bettina, and Abby worries about her marriage, sensing that Luka may have given up on it.

Neela's aortic rupture patient is in need of yet another follow up surgery, and they are starting to take a toll on her. Morris talks with a shrink about his experience with the jewelery thieves. Abby needs to make a tough decision when a new opportunity is presented to her.

When a drunk patient is admitted to the ER, his actions endanger everyone at County. Pratt is still pursuing his dreams of becoming Chief of the ER, and Gates is worried about his future with Sam. Luka unexpectedly runs into Dr. Moretti.

Abby awakens after the ambulance explosion and rushes to check on Pratt; Sam and Gates rush to the scene; Morris and Neela struggle to keep up with Pratt's injuries.

Everyone in the ER is trying to cope with the loss of their colleague. The staff feels defensive toward the new Chief and her tough disposition. Gates and the new interns treat a bio terrorist, who has a lethal secret that endangers them all. Neela makes a great effort to get Dubenko back on the surgery staff, and gets help from an unexpected souce.

Neela is upset when she finds out Abby's good news second hand; the new chief, Catherine Banfield, and Abby disagree on how to treat a gunshot wound victim; Abby defends Sam when she goes before a nurses disciplinary board.

Banfield is caught off guard when a man tries to steal her wallet; Dr. Dubenko returns to the surgery team; a family member is suspected of hurting a young gymnast; Sarah gets her tongue pierced.

Sam's time is taken up by her studies for a pharmacology exam, leaving Gates feeling neglected. A school fight results in a stabbing, with Brenner treating the victim and trying to uncover the truth behind the story. Morris has a surprise for Neela. Gates gets locked in a stairwell with a quiet young boy on Halloween night.

Dr. Banfield is irritated when Morris takes Chaz under his wing and teaches him risky medical procedures; Neela is unhappy when Dr. Banfield undermines her authority with an intern.

Dr. Banfield takes a run to clear her head but finds herself trying to rescue a three-year-old girl from drowning in a nearby lake. Gates tries to pull some strings in the ER to help his homeless war hero. Banfield is reminded of her own experience at County with Dr. Greene caring for her son as she tries to save the young three-year-old girl from certain death. Meanwhile, the interns continue to struggle to keep up in the ER.

Sam gets frustrated with Gates when he gets obsessed with finding a homeless war hero. Neela is upset at her intern after he gets the entire surgery department into a lawsuit. A husband and wife come into the ER after someone tried to burn down their home. Brenner loses his cool with a patient and it gets physical.

Banfield and Morris go to the coffee shop at 3 a.m. and are served by 20-year-old Debbie who is six-months pregnant. The doctors treat someone with a heart problem and Alex. Chaz must look for a missing 7-year-old boy who saw his sister die.

Morris' father arrives at the ER's doorstep and leaves him an unwanted package. Sam wants Alex to get off the ventilator as quick as possible following his accident. Meanwhile, a woman is in danger of being deported despite her high-risk pregnancy.

Alex is set to be released from the hospital. Doctors treat African-American brothers Curtis Bennet, 17, who has abdominal pain and 10-year-old Quincy Bennet who has a knee injury. Both were injured during a drug deal that went terribly wrong. There's still some residual tension between Gates and Sam. A female patient in police custody doesn't want to be examed by Morris. A 13-year-old patient named Anastasia messes with Neela's love life.

Neela has a recurring dream; Gates tries to save a patient who jumped out of a window while sleeping; Neela is surprised to see Dr. Corday.

Morris tries to help a girl who was hit while riding her bike; Gates can't get over his feelings for Sam; Neela is flustered when Dr. Brenner returns from Australia.

Morris and Gates treat an older man who was assaulted on the street; Sam gets a surprise visit from her sister; Dr. Morgenstern visits County General when he discovers an old mentor is ill.

A mother is severely injured by a car accident in the ambulance bay; an insurance company frustrates Morris; Neela tells Brenner about her offer in North Carolina.

It's Valentine's Day. Dr. John Carter is back at the County. Brenner and Neela are getting closer. Dr. Banfield is having a hard time trying to have a baby. And Puck and mushrooms may not be a good combination.

Carter finds himself struggling with County's new technology and procedures. After becoming frustrated with the in vitro-fertilization, Banfield and her husband discuss adoption as an option. Sam's mother arrives in an altered state of mind.

A camera crew interviews the staff at County General for a documentary on emergency medicine. Morris’ cop girlfriend gets injured on the job and is rushed into the ER with gunshot wounds. Neela wonders why her relationship with Brenner lacks so much communication. Sam struggles to make amends with her mother.

Neela and Sam are shocked when they arrive back to the airport with transplant organs only to find that their plane has left them. Dr. Carter gets a surprise visit from an old friend while waiting for his kidney transplant. Dr. Banfield bonds with an abandoned baby boy that is left at the ER.

On Neela's last day at County, she has doubts as to whether she is making the right decision.

The ER doctors and nurses help out at Camp Del Corazon, a camp for kids who have had open-heart surgery, working alongside the camp counselor.

As Carter prepares to open a new facility for the underprivileged, some old friends/colleagues gather. Rachel Greene, Mark Greene's daughter, applies for an internship at County.