Alan fields a difficult request from Shirley after her father suffers an injury while in the late stages of his battle with Alzheimer's; Carl represents a group of Nantucket residents who are concerned about homeland security; Jerry's new girlfriend sues him for sexual assault.

When Denny receives bad news about the state of his Alzheimer's, Alan goes before the Massachusetts Supreme Court to plead for access to an experimental drug that could help his condition. Meanwhile, Jerry and Katie try to help a girl get into Harvard after her SAT scores arouse suspicion, and Catherine Piper returns.