Pilot Episode: Working out of a patrol car designated "Adam-12," Officers Malloy and Reed perform a typical day's work, which includes a high speed auto-chase, the capture of two robbers, and an emergency call to save a suffocating baby. Malloy decides to turn in his badge after his young partner was killed a few weeks earlier. But at the end of the shift, he comes around and decides that he can't let inexperienced Jim Reed loose on another officer, so he decides not to leave the force.

Malloy and Reed learn of a serial home burglar stealing color TVs. They stumble upon the suspect's car with unusual results. Also, Reed must come to terms with his anger over a drug using mother that endangered her children to score dope.

Officers Malloy and Reed are involved in a high speed chase, a murder case and a family dispute as they work the P.M. watch. Reed worries all evening that the small dent in the fender he caused while backing the car up for fuel might lead to termination, since he is still on probation.

Officers Malloy and Reed assist a young mother whose baby is threatened by a deranged man and they help a woman being harassed by a spiteful neighbor.

Officer Reed learns that a professional officer has to keep their emotions under control; even when confronted with an abusive drunk-driver, right after clearing an "officer down" call & finding his close friend from the Academy critically wounded.

Officers Malloy and Reed look for a robbery suspect, help a woman pinned under her crashed car and settle a family dispute, among other duties.

In an episode where Reed learns to keep his wits under control, the officers deal with a loud noise complaint where an elderly woman refuses to answer, much less acknowledge, a teenaged girl's desperate pleas for help after the woman learns she was at a house where loud party music is being played, and it leads to a tragic drowning of a 4-year-old girl in a backyard swimming pool. Other calls include a brawl at a pop-spirituality temple on the verge of a schism over meditation styles, and a misused silent alarm at a liquor store.

Malloy teases Reed about calculating the cost of a new house while their first baby is still 6 months away. In the meantime they settle a domestic dispute between arguing neighbors, help a taxi driver that was just robbed, and a local man mistaken as the President by a group of rural Mexicans. Finally, they must arrest a psychotic shooter holed up in his house.

Reed gets Malloy to agree to an early dinner when his wife puts him on a low-cal diet. However, one after another event prevents them from going code 7 all night long. Events include the theft of a man's sod, stolen credit cards, and a suspected car theft.

Reed tries to pawn off his new litter of puppies to co-workers, strangers, even victims. The officers work a silent alarm, rescue a boy with his head stuck in a fence, and track down a prowler.