The FBI becomes involved when the bodies of young Asian girls are washed up on the beach. The situation becomes more critical when it is discovered one girl has avian flu. As the investigation continues, Don and his team discover a connection between the girls and the sex trade industry. Meanwhile, Amita considers a transfer to Harvard University, which causes Charlie to re-evaluate his feelings for her.

The case of a dead minor league baseball player leaves Don and the team with more questions than answers. When Charlie discovers that someone has come up with a statistical analysis that can identify which of the players are on steriods, the case gets more leads...and a suspect.

One of David's closest friends is called into question after a man dies while boxing with him. When it turns out this is not the first time such an event has happened, things look even worse. Charlie is busy practicing what little he knows about poker, so he can take Larry's spot in a tournament.