Astronaut Molly Woods tries to reconnect with her husband, John, and son, Ethan, after returning from a 13-month solo mission in outer space. Molly’s mystifying experiences in space lead to events that will ultimately change the course of human history.

Molly has to decide if she is going to reveal her pregnancy to John after he confronts her about her distant behavior. Meanwhile, John and Molly face parents who are suspicious of Ethan when he goes to school for the first time.

When Sparks falls under the influence of the vision of his deceased daughter, he flees with Molly’s baby to a remote location. Now, Yasumoto and Molly must rely on each other to track down the offspring.

Molly returns to space in an attempt redirect the Seraphim away from Earth and protect the world’s population from the deadly spores. Also, John discovers that Odin's plan has put Ethan in terrible danger.

Molly and J.D. discover another pregnant woman who is suffering from inexplicable and fatal symptoms. Meanwhile, Molly begins to question her own mental stability. Julie struggles with Ethan's rebellion.

Molly, JD and Ethan track down John’s mysterious former colleague who may hold the key to stopping the Humanich threat. Also, Julie enlists Charlie on a mission to find out where Lucy’s orders are coming.