Ryuko Matoi is a vagrant school girl traveling from place to place searching for clues to the truth behind her father's death - the "woman with the scissor blade". The journey leads Ryuko to Honnouji Academy.

Sirens awaken the No-Star students for the start of “No-Late Day,” where being tardy will get you expelled from Honnouji Academy. With Senketsu in the wash, Ryuko must fight on her own to get through the Discipline Committee’s traps and arrive on time.

Honnouji Academy is mobilizing for the Tri-City Schools Raid Trip! But after her recent rampage, Ryuko is moping in bed, unwilling to fight. However, Shinjiro Nagita, formerly with the Newspaper Club, is determined to get her back into uniform!

Ryuko's rampage continues, and thanks to Ragyo and Nui she has an unexpected new ally. With Satsuki as the target, will the Elite Four and Nudist Beach be able to withstand the onslaught?

The final confrontation is at hand! Will Ragyo and Nui bring on the end of the world, or will Ryuko and the others be able to stop them?