Archer and Asher clash over a patient with close ties to Goodwin. After a patient is shot during a home invasion, Scott and Marcel help with the investigation. Maggie and Halstead work to protect a patient who is in the country illegally.

Halstead and Asher clash over a patient in need of a kidney transplant. Marcel faces a tough decision when Blake is in surgery. Choi and Archer treat the son of Med's general counsel. Med's family grows.

Goodwin is worried after an accident lands two people close to her in the E.D. Archer returns to Med and treats a man concerned about a family curse. Maggie and Ahmad help a patient on a cross-country road trip.

Ripley and Charles treat members of a cult. Ahmad's suspension takes an unexpected toll on Marcel. Abrams' 5-month-old son lands in the E.D. under questionable circumstances.

Ripley and Charles treat a high-risk prisoner who may have dementia. Archer and Sean clash when a resident from Margo's facility lands in the E.D. Marcel receives shocking news.