When an unexpected piece of evidence surfaces in the 305, Rosewood and Villa attempt to solve a serious crime involving a very well-off Miami man. Meanwhile, Rosewood struggles to balance a new romantic interest with the demands of his mother, and Villa runs into trouble on the job.

A series of mysterious deaths pulls Rosewood off the glamorous promenades of South Beach when a troubled young genius stands accused of murder, and the only one who believes in his innocence is Rosewood. He must contend with a colorful new adversary, escalating health problems and a burgeoning romantic relationship, while Villa's inability to connect with people hampers her own ability to investigate the case.

Rosewood and Villa must prove a brilliant doctor murdered two patients, despite a limited amount of evidence; Rosewood receives a letter containing potentially life-altering news.

Rosewood and Villa seek justice for a murdered ex-con who had ties to a Little Haiti gang; Villa struggles with her recent dreams; Rosewood faces an unexpected turn in his relationship with Kat.

Rosewood and Villa dive into the hip Miami art scene to catch a serial killer who is on the cusp of creating a "masterpiece." Meanwhile, an impending lawsuit against Rosewood threatens the lifeline of Magic City Lab, and Rosewood tries to protect Villa from his best friend, Mike.

Rosewood and Villa must follow a trail of clues left for Rosie, before another victim falls prey. As things heat up between Villa and Mike, Villa escapes by throwing herself deeper into the case, which inevitably pushes her closer to Rosewood. Meanwhile, Donna intervenes when Pippy decides to give TMI’s absentee mother a piece of her mind. Plus, the Chief position is Hornstock’s, if he is willing to pay a stiff price.