Phillip's religious beliefs and Jeffrey's grief over the death of his son put them on opposite sides of whether to convince a young mother to remove her infant from life support so that her daughter's organs can be donated to save the life of another baby; Karen deflects a flirtation from Jeffrey, but romantic sparks fly between her and Aaron.

The staff has its hands full when a man suffering from the after-effects of taking amyl nitrite suffers one complication after another, thereby necessitating multiple surgeries, and Alan takes one for the team right on the nose when he strains credulity in attempting to put the patient's situation in the best possible light; Geri and Jeffrey make peace; Camille contemplates having some plastic surgery after Aaron suffers from performance anxiety on their first post-reconciliation date; Jeffrey agrees to help Laurie put on the Institute's Christmas concert, but the preparations for the event begin to overwhelm her and put additional strain on her already fragile state; Danny and Maggie can't keep their hands off each other; Jeffrey confesses his despair about Laurie's condition and its effect on his life to Camille.