When the bodies of two missing deputies turn up, it points to a serial killer who has been terrorizing the northwest. Volchek assigns the investigation to Vinnie when Stem loses control. Frank warns Vinnie he has to leave after Dan tells him there's a 40 man task force on the way to Lynchboro. As Volchek tries to eliminate possible suspects, Stem confesses to the murders, then electrocutes himself. Vinnie flashes back to Sonny killing himself, then snaps and takes off, stealing Frank's car.(source: http://www.plasticcow.com/wiseguy)

Vinnie calls in Roger Lococco to take over the case, then holes up in a seedy hotel in Seattle. Frank is more interested in looking for Vinnie than in nailing Volchek. Paul orders Frank to continue the case and offers him another agent, which Frank refuses. Roger takes over as sheriff. Dan moves to Seattle to support Frank and look for Vinnie. (source: http://www.plasticcow.com/wiseguy)

Vinnie takes a job hauling hospital waste as he continues to hide out in Seattle. Frank finds out Volchek is going to bribe a state official to get the license for his hospital and plans to arrest them after dinner. Roger uncovers Volchek's cryogenic vault. Lacey talks to Roger about how important Volchek is to the town, causing him to throw the arrest. (source: http://www.plasticcow.com/wiseguy)

Volchek becomes depressed over losing the hospital. Roger and Frank try to save Lynchboro by getting Volchek to realize he really is in control. Vinnie goes to Kousakis when he realizes the waste they're dumping is causing a hepatitis outbreak in a nearby school, then attacks Kousakis when he tells Vinnie to mind his own business. Vinnie tries to alert an official to the toxic waste, but it turns out the guy is corrupt and tells Kousakis to kill Vinnie. Feeling trapped, Vinnie kills the two gunmen sent to kill him, then flees into the night. Roger leaves, telling Frank to tell Vinnie they're now even. (source: http://www.plasticcow.com/wiseguy)