Driven out from his orphanage, Nakajima Atsushi wanders the streets of Yokohama on the bring of starvation. Determined to live, a chance encounter with a drowning stranger changes his fate...

Now an official member of the Agency after passing their entrance exam, Atsushi is assigned to his first case right away with Tanizaki and Naomi. Though deceptively simple on the surface, there's more than meets the eye...

The Agency investigates a series of disappearances in Yokohama. Kunikida enlists the help of a hacker named Taguchi Rokuzou, but all they find are photos of the victims and mention of a mysterious figure called the Azure Messenger. They follow the trail of clues to an abandoned hospital...

Dazai goes missing, but the Agency operatives feel it's just business as usual. Meanwhile, Atsushi accompanies Yosano Akiko on a shopping expedition, where they are suddenly plunged into the middle of a terrorist bomb threat by one of the Port Mafia...

Francis, the leader of The Guild, a North American organization of gifted members, is the one responsible for the bounty on Atsushi's head. Fukuzawa refuses Francis's offer to buy out the Agency, but their agents begin to disappear...

The Port Mafia's council of five top executives has decreed that Mimic must be annihilated. In the ensuing battle, Odasaku has a fateful encounter with Gide, the leader of Mimic, who makes a cryptic prophecy. Night falls, and the usual bar now awaits Dazai, Odasaku and Ango...

Mori, the leader of the Port Mafia, sends a letter to Margaret M. and Nathaniel H., threatening to destroy them and the ship they are protecting.

The leaders of the Agency and the Port Mafia negotiate an alliance. Meanwhile, Dazai and Chuuya face off against Lovecraft.

Atsushi searches desperately for the control terminal, which he would need to stop the Moby Dick from crashing into Yokohama. He's greeted by Akutagawa and Francis, both of whom have other plans in mind.

Atsushi and Akutagawa fail to call off the Moby Dick's descent. They search desperately for other ways to protect Yokohama.

Port Mafia leader Mori Ougai orders a fifteen-year-old Dazai Osamu to investigate the appearance of a certain individual in the Yokohama Settlement area.

Nakahara Chuuya and Dazai Osamu reveal the truth behind Arahabaki, Randou, the former Port Mafia boss and Chuuya himself.

Louisa reunites with Fitzgerald, but he’s not quite the man he used to be.

The Detective Agency president is in safe hands for now, but unless he or the Port Mafia boss dies, a full-scale war between the two organizations is inevitable.

Mori Ougai and Fukuzawa Yukichi fight to the death in a desperate bid to save the organizations they lead from falling into a devastating war.

The gifted responsible for the virus is on the run as Nakagawa Atsushi and Akutagawa Ryunosuke chase after him. Meanwhile, the Detective Agency has the Rats’ hideout surrounded to try to capture Fyodor Dostoevsky.

Rampo gets a ride to the police station, but the officer doesn’t seem to be who he says he is.

The last page of the manuscript received by Poe appears to have been a photocopy. Rampo seems to know why, but there are still more mysteries surrounding the death of the author.

Teruko goes head-to-head with Sigma. Tachihara rethinks the Agency’s innocence after re-infiltrating the Port Mafia.