Boruto and Sarada sneak out of the village and head to Orochimaru's research lab to find clues about Mitsuki. After evading the ninja guarding the entrance, they get in. But what they observe at the facility and hear from Orochimaru makes Boruto realize that he never truly knew Mitsuki. Meanwhile, the village finds out that Boruto and Sarada have gone in search of Mitsuki, and Shikadai and his Team 10 are assigned a tracking mission to bring back them back.

Jugo is suffering from the effects of the drug that activates the power of the cursed seals. Somehow or another. Boruto and Suigetsu want to try to save him, but they are rendered unable to move because of being injected with a tranquillizer. Meanwhile, it’s time for the migratory birds to set off.

Mirai leaves the inn with Tatsumi without telling Kakashi and Guy. At the hot springs Mirai thinks she sees her father Asuma, but something feels off. Will Mirai be able to get back to her escort mission in one piece?

Boruto manages to reach Sasuke, but he sees his mentor disappear before his very eyes due to an attack by Urashiki Otsutsuki. It turns out that Sasuke, along with the Kazekage and Shinki, was in the middle of battling Urashiki, who was pursuing Shukaku, the One Tail. Gaara uses a Sealing Jutsu and manages to stop Urashiki, but he believes it’s only a matter of time before the jutsu is broken. He orders Shinki and Boruto to go to the Leaf Village to keep Shukaku safe.

Urashiki appears to steal the chakra of Nine Tails from Naruto, but his attempt is unsuccessful. In order to save Naruto, Boruto, Sasuke and Jiraiya pursue Urashiki. Jiraiya then notices that the malevolent Nine Tails Chakra has started filling the air.

Boruto and his team try to get Kokuri assigned to the same cell, but the warden, Benga, shuts the idea down. Looking for a weakness in Benga, they approach Doragu, the leader among the prisoners, for information they can exploit. Doragu is willing to give them information, but in exchange Boruto and the team must undergo a test of perseverance.

Boruto's new mission is to guard Tento, who is obsessed with ninja and collecting X Cards. He begs Boruto to teach him ninja skills, and Boruto thinks this will be a good opportunity to knock some sense into Tento. Meanwhile, the Mujina Gang, which had been laying low after Team 7’s infiltration mission at Hozuki Castle, rears its ugly head.

Cho-Cho and Choji go to the sweet shop after their training session, only to be disappointed that they are unusually out of azuki bean sweets. After hearing thieves have been raiding the deliveries, Cho-Cho plans to team up with Anko Mitarashi, her friend in desserts and beloved Ninja Academy instructor, to protect the azuki beans that she loves, and capture the bandits!

Boruto and the team finally find the missing researcher. Despite his resistance, the team is determined to take him back safely to their client.

Boruto and the others manage to escape Yuuga's barrier, but this time his younger brother Hiruga gets in their way. Like Yuuga, Hiruga will resort to any method to fulfill his mission and uses his jutsu to seal away Boruto and the others. As Boruto tries to break the jutsu, he’s baffled by their rabid fighting style and their willingness to risk their lives.

Inizia la resa dei conti tra il Team 7 e Ao! Il Team 7 lavora insieme per lanciare una raffica di attacchi, ma contrastare l'uso abile degli Strumenti Ninja Scientifici da parte di Ao non sarà facile. Proprio mentre sembrano averlo messo alle strette, Ao rivela la sua arma più grande.

Delta si fa strada nel Villaggio della Foglia per riprendere Kawaki e appare davanti a Boruto e agli altri. Naruto la affronta per proteggere Boruto, Himawari e Kawaki. Attacca Naruto con strumenti ninja scientifici che sono stati impiantati nel suo corpo pesantemente modificato. In risposta, Naruto scatena il potere delle Nove Code, e ne consegue un feroce scontro!

Attraverso la fessura della stanza, Boruto, Kawaki, Sarada e Mitsuki entrano nella dimensione in cui si trova il Naruto sigillato. È sorvegliato da Boro, che è anche lui dopo Kawaki. Si svolge una battaglia tempestosa.

Naruto e gli altri sono esausti dalla loro battaglia con Isshiki. Improvvisamente, Boruto attacca Sasuke. Momoshiki ha preso il controllo della coscienza di Boruto e si trova davanti a loro come un nemico. Kawaki chiama disperatamente Boruto per farlo uscire. Sfortunatamente, le sue parole non sono in grado di raggiungerlo. Sasuke dice a Kawaki un modo per riportare la coscienza di Boruto. Per salvare Boruto, Kawaki tenta un piano rischioso usando un jutsu che ha imparato solo di recente. Mentre Kawaki e Sasuke combattono una battaglia disperata, Naruto alla fine esaurisce le forze. Mentre la sua coscienza svanisce, lui e Kurama ricordano tranquillamente il loro passato.

Kae has been taken away and Kawaki must face a dangerous assassin. Himawari acts as his partner and provides support during the battle. They try to corner the enemy with coordinated attacks, but the enemy proves to be powerful. Meanwhile, their classmates, who had entrusted Kawaki and Himawari to directly confront the assassin, take action in a desire to try to help. Will Kawaki be able to save his precious friends and accomplish his mission?

Naruto falls ill, and Sasuke goes to the Tatar Observatory to try to find a cure.

Sasuke and Sakura work together to gather information concerning the Ultra Particles. Unfortunately, there is still much they don’t know, and they are unable to figure out where to get answers. Eventually, Sasuke finds a clue to the whereabouts of the Ultra Particles from something his cellmate mentions. Meanwhile, Sakura discovers a hint to unraveling the mystery of the Map of the Heavens from a game called Star Lines. Having finally gathered the information they need, Sasuke and Sakura try to obtain the Ultra Particles. However…