Rachael Leigh Cook smashes more than eggs in her latest This Is Your Brain on Drugs public service announcement. Optimus Prime, leader of the Autobots, falls prey to prostate cancer. The outcome is never in doubt during "World's Most One-Sided Fistfights Caught on Film." Outtakes from The Dukes of Hazzard, The X-Files, Battlestar Galactica and more come to light in "Bloopers."

Voltron engages in an old-school dance-off in "You Got Robo-Served." The secret lives of nature's most fascinating beasts are exposed in "Secrets of the Animal Kingdom." Testicles are terrorized in "Ode to the Nut Shot." Walt Disney's severed head with its giant robotic spider-body attacks Cuba. See how much the kids are horrified in "Scary Barney"

The animals Noah left behind try to survive the flood in their very own ark. Enjoy instant nostalgia with "That '00s Show." Mrs. McNally's third-graders produce an animated abomination in "The Best Cowboy." The world's most famous cars, from KITT to the General Lee and even Mario karts, race against each other in "3 Fast 3 Furious."

Seven of the world's greatest heroes stop being polite and start getting real in "The Real World: Metropolis." Icons from Star Trek and Tiger Beat alike unite for canned sitcom laughs in "Two Kirks, a Khan and a Pizza Place." Jesus Christ hunts down his greatest nemesis, Tarantino-style in "Kill Bunny." The hottest game show from Japan is here: "Who Poop Last?!" The legends of rock 'n' roll return from beyond the grave to haunt the "Zombie Idol" reality show.

Robot Chicken's Christmas "whodunit" spoof. There's been a murder on the North Pole Express and since each passenger could be the killer only Jesus can solve this tough case with many twisty turns. The suspects include Santa's frienemy Krampus, Santa's stereotypically Jewish nutcracker accountant called Nutsy Goldberg, Snowball the snowman, Santa's inquisitive reindeer Comet, Christmas elf Peppermint, Santa's gingerbread girlfriend and singer Ginger, the train's accommodating porter and, of course, Tim Allen.