As his clinical begins, Devon treats his first patient with a revolutionary medical fluid that doesn’t go as planned. Meanwhile, an overdosed John Doe is rushed to Chastain, leading Conrad straight into a much bigger scandal than he expected. Then, a shocking secret regarding Cade’s past is discovered.

A young boy comes into the hospital with a rare disease which leaves his bones incredibly fragile; with his clinical trial officially being declared a success, Devon has some huge decisions to make about the future of his career.