Når et leilighetskompleks blir ødelagt i en bombeeksplosjon, etterforsker FBI-agentene Maggie Bell og Omar Adom «OA» Zidan en mulig gjengkrig – helt til deres hovedmistenkte blir funnet død.

Etter at åtte personer blir forgiftet ved et spisested i New York, sporer Bell og Zidan ugjærningen til en usannsynlig gjerningsperson.

Teamet etterforsker drapene på 18 unge kvinner ved hjelp av en rådgiver knyttet til de avdøde.

Bell og Zidan sporer opp en krypskytter med et økende antall døde på samvittigheten.

FBI-agentene Maggie Bell og Omar Adom Zidan etterforsker drapet på en kjernekraft-inspektør.

Etter at en senators datter blir kidnappet og det kreves løsepenger, må FBI finne den lille jenta før tiden løper ut. De må grave i senatorens fortid for å finne ledetråder til hevm som har gjort dette mot familien hans.

Kriminelle, utkledd som NYPD-betjenter, raner pansrede biler.

Agent Bell og Zidan leder letingen etter en bortført kjemiker, som har jobbet med kjemiske våpen.

En politimester og et nøkkelvitne blir drept i et bakholdsangrep, og Maggie og OA må finne personen som lekket informasjonen som ledet til drapene.

En ulovlig våpenhandler, som har angitt informanter, blir drept. OA, som er den eneste agenten som likner på ham, går undercover for å stoppe våpensalget.

Når en dommer og datteren hennes blir drept etter at hun dømmer en mann til fengsel, leter Maggie og OA etter morderen. Dana har en historie med offeret, og en interesse i saken.

Når en provokatør blir drept etter å ha holdt tale ved et universitet i New York, etterforsker Maggie og OA skolens mer ekstreme politiske grupper og støtter seg på OAs studentsøster for å få hjelp.

Maggie og OA er på oppdrag for å finne et par som står bak vold og væpnede ran som har ført til at en politibetjent ble drept.

Etter at en underøkende journalist blir drept, avdekker teamet informasjon som kobler den mistenkte til tidligere saker. Offerets død minner Maggie om reporterektemannens død.

Mye tyder på at en seriebomber sikter seg inn mot Wall Streets elite. Maggie og OA leter etter en mistenkt som virker oppsatt på hevn. Dana jobber med Spencer Briggs, en merkeig profiler som skal hjelpe til i saken.

Når datteren til en velstående familie blir kidnappet i et forsøk på å bli internettkjendis, oppdager Maggie og OA at kidnapperens plan går mye videre enn bortføring for å bli husket for alltid.

Maggie og Dana kjemper for rettferdighet for en seriemorders ofre, men borgermesteren begrenser etterforskningen for å kutte kostnader.

OA og Maggie slår seg sammen med medlemmer av FBIs Fugitives Department for å finne en person mistenkt for drap, som settes på listen over Amerikas mest ettersøkte.

Teamet må spore opp en farlig narkotikaring etter at en amerikansk diplomat blir drept. Jubal og OA prøver å hjelpe gamle venner å bli kvitt sine indre demoner.

Når en kontroversiell leder fra Egypt kommer til New York for å gjennomgå en hjertetransplantasjon, sliter OA med å balansere sin personlige mening med sin profesjonelle plikt når han skal stå for sikkerheten.

Etter at en dekorert FBI-agent blir drept, etterforsker teamet saken og finner ut at mannen levde et dobbeltliv. Maggie sliter med hviken informasjon hun skal avsløre for agentens enke, som også er hennes personlige venn.

En kvinne med informasjon om Maggies ektemanns død blir bortført, og teamet avdekker en kriminell operasjon som er større enn noen hadde forestilt seg. Dana setter karrieren i fare ved å tillate Maggie å jobbe med saken, som er så personlig for henne.

After a bomb detonates at a restaurant in Queens, the case becomes personal for OA, who grew up eating there. But what initially seems like a terrorist attack reveals itself to be more complex, and OA goes undercover to prevent another incident.

After the son of a prominent Mommy blogger is kidnapped, the team must sweep through her two million followers to find the culprit. Kristen continues to adjust to life as a field agent with her new partner.

After a front-running female presidential candidate, Valerie Caldwell, is targeted with a car bomb, OA and Maggie must hurry to track down the bomber before they strike again. The case leads them to wonder whether this person is targeting Caldwell for her political aspirations or something else.

After a shooting at a nightclub, it appears that the FBI may have ignored previous threats from a local white supremacist group. Also, Kristen wrestles with her commitment to the Bureau and her responsibility to her community.

A loving husband and father of two, Jim Russo, is kidnapped after accidentally getting involved in illegal dealings far beyond what he imagined. Also, Jubal must make a difficult decision regarding his family and their future.

After a Wall Street investor is murdered, the team is led to an insider-trading ring that uses unconventional methods to gain information. OA struggles to maintain confidence in his budding relationship with Mona.

When a board member of a soon-to-be-public medical tech company is murdered, the team tries to find out who had the most to gain from his death. OA is conflicted when pressure to help a family member is at odds with his commitment to tell the truth.

A car crash results in the death of a photographer; Maggie sympathizes with his widow when she notices similarities with her own husband's death.

After an altercation with a student, a teacher goes missing, leading the team to investigate everyone who might have had a grudge against him. Also, a key witness in the case steps up to help, and Maggie does whatever she can to ensure their safety.

A former kidnapping victim is linked to a series of murders that includes the daughter of an NYPD detective. Also, Kristen begins to doubt her ability as an agent after a training exercise leaves her shaken.

After a businessman with a history of harassment claims against him is killed, the team suspects the killer may be one of his many accusers.

A bank holdup leads the team to a safe deposit box, the contents of which have the potential to destroy national security; Kristen is eager to get back into field work while other team members still have their concerns.

The son of a retired FBI agent is kidnapped, and the team must investigate if it's an act of revenge; Isobel must make a hard call when information from the past comes to light.

When a U.S. attorney is found dead steps away from the body of a private escort, the team must piece together what connected the two seemingly random victims. Also, Jubal’s connection with one of the victims makes finding the killer much more personal.

After a truck filled with armour-piercing rifles is hijacked, the team works to discover who stole it, and what they have planned for the stolen weapons. A friend from OA's past returns to help with the case, but OA isn't sure he can trust him.

After the police ignore a desperate father's plea for help, he abducts a billionaire's daughter and holds her hostage in a near-impenetrable safe room until his own missing child is returned to him. Also, Jubal puts his hostage negotiation skills to the test.

When the team is called to the scene of a murder, they quickly suspect political motivation, but when another murder occurs, they work to uncover a common thread before more bodies pile up. Also, Maggie contemplates a decision that could affect her entire career.

Jess LaCroix and his team come to help OA find a fugitive LaCroix arrested years ago after a bus with 26 students goes missing and he's the main suspect.

The crossover continues on FBI: Most Wanted S01E09 Reveille (II).

The FBI team investigates a drug deal gone bad after the body of a college student is found. Also, Detective Hailey Upton temporarily joins the team and finds her usual investigative methods clash with the Bureau's more buttoned-up environment.

The team welcomes a new member, Special Agent Tiffany Wallace, as they search for killers who orchestrated a mass shooting at a media company, and OA’s personal connection with the case threatens to cloud his judgement.

The team races to stop an active serial killer after three women are found weighted down at the bottom of a lake, and Jubal looks into an old closed case after there are multiple similarities to the recent victims.

When the leader of a drug cartel and one of the world's most wanted men, Antonio Vargas, is apprehended by the team, the entire FBI headquarters is put at risk when his henchmen unveil a terroristic threat to free him. During the turmoil, Isobel must make the difficult decision whether to sacrifice her conscience or her career.

A shooting at a quinceañera leaves two dead, but the team believes they may not have been the intended targets. Also, Maggie is trapped between a rock and a hard place as the team decides the best plan of action for using a witness to take down the suspect.

As the team searches for a young girl who was kidnapped from a cabin during a family vacation, they discover that the abduction may be tied to a skeleton in her family's closet. Also, Maggie questions her relationship with Nestor when she learns he hasn't been completely honest with her.

The team must infiltrate a drug trafficking gang after the robbery of a chemical plant leaves two customs agents dead. Also, Nestor offers his help on the case, giving Maggie new insight into his character.

As the team hunts a killer who is fatally shooting seemingly unrelated targets, an experience on the job has new agent Tiffany Wallace examining the tension between her career as an FBI special agent and the responsibility she feels to her community as a Black woman.

After a bomb leaves three people dead, the team presses a reluctant informant to gather information from his close friends who are under suspicion. Also, OA finds tension in his relationship with his girlfriend, Mona, when they clash on where the informant’s rights lie.

When a political reporter is kidnapped and held without a ransom demand, the team must dig into her past relationships in order to pin down her assailant’s motive. Also, Isobel’s relationship comes under fire when the case makes a connection to her boyfriend, Ethan.

The team must track down two assailants who wear animal masks while committing armed robberies, with the latest leaving an off-duty 26 Fed security guard dead. Also, Tiffany and Scola butt heads on whether or not to accept the local NYPD’s offer to help in the investigation.

After a man is killed by an explosive package shipped to his home, the team attempts to capture the sender and intercept his latest deadly parcel. Also, Maggie tries to trust her younger sister, Erin, is truly staying out of trouble as a new college student in NYC.

The team rushes to track down two doctors abducted by a desperate father willing to do anything to save his son. Also, Jubal's uncertainty in his family life affects his judgement during the hostage situation.

When the CEO of a major brokerage firm is shot and killed while surrounded by protesters, the team looks into who had the most to lose from his company's perceived manipulations. Also, Scola's previous Wall Street career and the reasons he left come to light as the financial details of the case begin to unfold.

While investigating a mass casualty incident at a New York City restaurant, the team scrambles to determine if it was racially motivated and if there was more than one gunman. Also, Maggie starts to notice troubling behavior from her co-worker, Elise.

When five prominent men are killed at a trendy New York City restaurant, the team’s investigation brings them into contact with a lieutenant in Antonio Vargas’ cartel, triggering a long-awaited showdown between Isobel and Vargas.

After a young woman is killed on her way home from a lavish yacht party, the team investigates who she was and how she came to be at the event, which was attended by some of the most influential people in the world. Also, Maggie brings Crosby into the investigation after a murder suspect is identified as a veteran who had been on several Army operations with Crosby.

The crossover continues on FBI: Most Wanted S03E01 Exposed (II) and FBI: International S01E01 Pilot (III).

Maggie, OA and the team must stop a hacker who is disabling life-saving equipment in several New York City hospitals. Jubal's son waits for important surgery at one of the impacted hospitals.

The team finds a connection between bombings and a private veterans' club in New York City; Isobel tells a reluctant OA to recruit a former Army buddy for intel.

The team hunts for a serial killer who is targeting young, homeless men. Also, Tiffany and Scola don’t see eye to eye on how to handle the case or the difference between partners and co-workers.

After a suburban woman is kidnapped from her home, the team looks into trysts on both sides of a seemingly perfect marriage. Also, OA feels pressure from Mona to make changes in his career path.

The team must track down a shooter targeting detectives from the same precinct and unit, while facing mounting tension from the NYPD. Also, Tiffany finds that her NYPD roots may be influencing her view of the situation.

After a young girl is kidnapped from her daycare, the team must help her parents navigate a debt owed to the deadly gang in their neighborhood; Maggie struggles to focus on the case when her sister returns from rehab.

The team attempts to extract key information from a vulnerable 9/11 widow, Hannah Thompson, who is shocked that her new “boyfriend” is the manipulative leader of a terrorist group planning an attack. Also, Scola is reminded of his brother’s death on 9/11, and Tiffany worries about his emotional choices during the investigation.

After Rina is critically wounded while heading to work with Jubal, the team makes the chilling discovery that a vengeful Vargas orchestrated the shooting from behind bars and continues to target the rest of their team and their loved ones.

As the team investigates a string of jewellery store robberies that culminate in a double murder, they uncover a connection to a 16-year-old boy trying to survive the foster care system. Tiffany becomes personally invested after learning about the boy's ill-fated upbringing.

The team searches for an abducted college coed; Jubal has a tense encounter with Rina's mother.

Maggie goes under cover working in a bar to investigate an anti-government group that regularly gathers there; a single father on the periphery of the group begins to fear he's in danger of becoming collateral damage.

When a Muslim college student and his younger brother are murdered, the team connects with the outraged imam of OA's former mosque, who insists the victims were wrongly targeted as terrorists.

The team investigates an extremist gun group after an anti-gun lobbyist building is bombed; SAC Bashar dangles a possible promotion for OA.

The team realizes they have a cross-country serial killer on their hands; the case has ties to Isobel's father, Robert, and his hotel, leading to revelations about their fractured relationship.

After an immigration agent is fatally shot at a hockey game, the team attempts to find the shooter, who they believe may also be targeting Congressman Curtis Grange, who was at the same game.

When a young couple is found murdered in a New York City park after returning from vacation, the team searches for a suspect linked to the drug trade. Also, Scola turns over a new leaf when it comes to his relationships.

OA is forced to confront one of his biggest fears when the team discovers that deadly sarin gas may have been sold to terrorists.

When a morning show host is murdered inside her home, the team tracks the killer, who they realize is targeting powerful women. Also, things become awkward for Scola when Special Agent Nina Chase becomes part of the team during Maggie's recovery.

The murder of a TSA agent leads the team to hunt down a killer who is using drug mules to exploit airport security checkpoints. Also, OA struggles to cope with the aftermath of the sarin gas exposure and the 10th anniversary of his army friend's death in Afghanistan.

When a retired DEA agent is shot outside a bakery, the team works to determine if the victim’s past cases or current bouncer job are connected to the murder. Also, Nina and Tiffany clash over the use of an informant while they are paired during the investigation.

The team pivots when their sting operation to secure a massive bomb from an illegal broker leads them to discover that the device is already in the wrong hands. Also, Jubal’s promise to be present at his son’s birthday party is put to the test as the case continues to heat up.

When an officer is shot dead at a pawn shop along with the store’s owner, the team tries to figure out why a young, recent Ivy League dropout is tied to the crime.

As the team investigates a deadly robbery that garnered a cache of automatic weapons for the killers, they discover one of the perps is a classmate of Jubal’s son, who is reluctant to cooperate with the case.

The team investigates a series of brutal assaults; OA hides information about his own mugging.

When a wealthy accountant is gunned down for secretly testifying against a notorious drug lord, the team’s investigation leads Tiffany to ask for help from a friend who was formerly with the NYPD and is related to the dangerous crime boss.

As the team works to rescue a 5-year-old kidnapping victim, Scola suspects the boy’s mother isn’t being forthcoming about why her son was targeted. Also, Nina struggles to open up to Scola about matters in their relationship.

Maggie returns from medical leave in time to help the team investigate two homicides: a law student on track to attend the FBI Academy and a young man with possible gang ties. Also, an inadvertent revelation from Maggie causes OA to worry that she is rushing back into the job too quickly.

When a deadly truck heist arms the killers with enough ammonium nitrate to construct a massive bomb, the team discovers a link to a terrorist group Maggie is working to infiltrate.

A teen shows up at FBI headquarters with a large bag of fentanyl, seeking the team's protection from the men who shot his father; Nina goes to Scola with a proposal he is hesitant to accept.

The abduction of a young woman leads the team back to a cold case from 18 years ago, which pushes Isobel to reconnect with her old partner Jake and take another shot at solving one of her first cases in the bureau.

The team jumps into action when analyst Kelly Moran is taken hostage.

After a mysterious bioweapon leaves two MTA workers dead and one injured, the team rushes to determine who is behind the attack and the location of their next target; Jubal’s past demons begin to surface.

The team investigates the murder of a professional informant after he's found dead outside an abandoned factory in Red Hook. Also, Maggie reconnects with an old colleague and mentor.

After a string of armed robberies targets various businesses, the team investigates a suspect who leads them to something much bigger; OA worries about his future when his investments begin to go south.

When an off-duty diplomatic security agent is fatally shot in New York City trying to apprehend someone, the team investigates if there's a connection to his time working in Croatia.

The shooting of a federal corrections officer leads the team to an ex-Marine who has gone rogue ever since he returned from Afghanistan; Tiffany's sister looks to her for guidance when their younger brother begins to lash out.

To aid Scola in his undercover mission to find the terrorists believed to be behind the imminent attack in New York City, Maggie calls in Remy, whose well-connected informant from a prior case may be key to moving the operation forward.

The crossover starts on FBI: International S02E16 Imminent Threat (I). It continues on FBI: Most Wanted S04E16 Imminent Threat (III).

When the deputy commander of an Air National Guard Base is kidnapped and forced to give over access codes, the team must work quickly to find the suspect along with stolen ammunition. Also, Scola questions his own safety in the aftermath of a recent traumatic experience.

When a trucker is gunned down after a routine trip from Canada, all signs point the team to a noted criminal on the FBI’s Most Wanted Terrorists list. Also, Jubal gets to work with an old friend and colleague, Detective Jack Lombardo.

A drug dealer is shot in a federal park and the team sets out to look for his killer; Maggie's sister returns to New York and complicates the case.

All eyes are on the team when they try to find out who kidnapped the only child of a prominent U.S senator. The abduction also uncovers a potential link to a similar case that was pushed to the side by local authorities.

After finding a group of teens dead from a drug overdose, the team races to find the dangerous dealer and his supplier. Meanwhile, OA questions where he stands in his faith.

When a prominent doctor is found dead in a ritualistic slaying, the team must race against time to hunt down a religiously motivated serial killer. Also, Scola faces a life-or-death decision.

When a bus explosion kills several innocent people, the team jumps into action to take down the responsible terrorist organization. Meanwhile, Scola tries to balance fatherhood with the job.

After the president of the NY Fed is gunned down trying to help a young woman in peril, the team races to find the killer and the missing woman. Additionally, a distressing connection to one of Jubal’s past cases is revealed during the investigation, compounding the pressure on him as he also deals with his son’s school suspension.

When a local club owner is found dead, the team works quickly to find the motive behind the murder of a seemingly innocent man. Meanwhile, OA is smitten with a new love interest but is concerned that she's mixed up with the wrong crowd.

When a federal judge is gunned down execution-style in broad daylight, the team is sent looking for a suspect with ties to a local Islamic center. Also, Maggie reunites with a former colleague while things become tense between OA and his girlfriend Gemma.

When the director of a Brooklyn migrant center is abducted and held hostage along with his wife, the team must work quickly to meet the demands of their kidnapper. Also, Maggie picks Jessica's brain about motherhood.

After multiple people are targeted and killed with a poisonous gas in broad daylight, the team races to find the killer, who they believe is tied to an eco-terrorist plot. Meanwhile, Maggie continues to explore motherhood.

When a bombing at a local restaurant leaves several injured or dead, including a congresswoman and someone close to Isobel, the team races to apprehend the suspect before another explosive goes off.

After an employee of the U.S. Army is shot in an industrial park, the team works to track down the killer who reveals a larger plot at play. Meanwhile, Tiffany continues to struggle with the guilt surrounding Hobbs' death.

When a retired FBI agent is tortured and killed while working a security job, Scola and Nina go undercover as a married couple deep in the diamond game as the team tries to find out who is responsible. During the course of his and Nina's dangerous assignment, Scola is plagued by the possibility that their son Doug could end up parentless.

After an FDIC security guard is killed while tending to a pregnant woman in distress, the team works to locate the woman and the killer who took her hostage. Meanwhile, OA and Isobel worry about Maggie as she navigates taking care of Ella.

The team is thrown into a highly political case after four members of the Taliban are shot and one is kidnapped in New York with no record of their entrance into the country. Having served in the U.S. Army, this case hits close to home for OA, who struggles to open up to Gemma about his past in Afghanistan.

When a truck driver is murdered and the drug he was transporting goes missing, the team hunts for those behind the remaining batch that is already wreaking havoc on the streets of New York.

The Somalian terrorist group behind the death of Agent Hobbs resurfaces, sending the team on a chase to take them down for good.